Ramelteon (TAK-375) CAS 196597-26-9 Bohloeki >99.5% (HPLC)
Moetsi ea ka Sehloohong le Mofani, Li-Intermediates tsa Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Ramelteon |
| Litlhaloso tse tšoanang | (S)-N-[2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethyl]propionamide;TAK-375;TAK375;TAK 375;Rozerem |
| Nomoro ea CAS | 196597-26-9 |
| Nomoro ea KAtse | RF2885 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C16H21NO2 |
| Boima ba Molek'hule | 259.35 |
| Melting Point | 113.0 ho isa ho 116.0 ℃ |
| Ntlha e belang | 455.3±24.0℃ |
| Botenya | 1.119±0.06 g/cm3 |
| Potoloho e Khethehileng [α]20/D | -55.0° ho ya ho -60.0° (C=1, CHCL3) |
| Sollubility ka Metsing | Ha e qhibilihe ka metsing (11 mg/l 25℃) |
| Solubility | E qhibiliha ka Ethanol, Methanol, DMSO |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e Tšoeu ea Crystalline |
| Mokhoa oa Bohloeki / Analysis | >99.5% (HPLC) |
| Melting Point | 113.0~116.0℃ |
| Tahlehelo ka ho Omisa | <0.50% |
| Masalla a ho Ignition | <0.10% |
| Isomer Purity | <0.10% |
| Litšepe tse boima | <10ppm |
| Acidity kapa alkalinity | Ikamahanye |
| Ethanol | <5000ppm |
| Tšilafalo e le Mong | <0.20% |
| Litšila ka Kakaretso | <0.50% |
| Infrared Spectrum | E Ikamahanya le Sebopeho |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | API, e Amoheletsoeng bakeng sa Phekolo ea ho Insomnia |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Ramelteon (CAS: 196597-26-9) e ile ea amoheloa ka lekhetlo la pele ke US Food and Drug Administration (FDA) ka July 22, 2005, eaba e amoheloa ke Pharmaceuticals and Medical Devices Agency (PMDA) ka Apr 16, 2010. E ile ea ntlafatsoa le e rekisoa e le Rozerem® ke Takeda,e ka sebelisoa ho phekola lefu la ho hlobaela ka bothata ba ho robala, 'me e na le litlamorao tse hlakileng ho lefu la ho hlobaela le nako e khuts'oane.Sehlahisoa sena se ka khetha mofuta oa 1 le mofuta oa 2 oa melatonin (MT1, MT2), eketsa boroko bo liehang ba maqhubu (SWS) le boroko bo potlakileng ba mahlo (REW), kahoo bo fokotsa ho hlobaela.Ramelteamide ke setlhare sa pele se sa lemaletseng sa ho hlobaela se seng tlas'a taolo e khethehileng.Sehlahisoa sena ke melatonin receptor agonist.E na le kamano e phahameng le melatonin MT1 le MT2 receptors, 'me e na le phello e tobileng le e feletseng ea agonistic ho li-receptor tsa MT1 le MT2, empa ha e sebelisane le MT3 receptor.Ho phaella moo, ha e tlamelle ho li-neurotransmitter receptors tse kang GABA receptor complexes, 'me ha e kena-kenane le mosebetsi oa li-enzyme tse ngata ka har'a mefuta e itseng.Ka hona, e ka qoba tšitiso e amanang le lithethefatsi tsa GABA (tse ka bakang likotsi tsa koloi, ho oa le ho robeha).Joalo-joalo) le bokhoba ba lithethefatsi le ho itšetleha.Rozerem® e fumaneha e le letlapa le koahetsoeng ka filimi bakeng sa tšebeliso ea molomo, e nang le 8 mg ea Ramelteon ea mahala.Tekanyetso ea batho ba baholo e khothalelitsoeng ke 8 mg nakong ea metsotso e 30 ka mor'a ho robala.
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