Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Factory High Purity
Moetsi ea nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Rapamycin;Sirolimus;RAPA
CAS: 53123-88-9
Macrolide Immunosuppressive Agent
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | Rapamycin |
Litlhaloso tse tšoanang | Sirolimus;RAPA;AY-22989 |
Nomoro ea CAS | 53123-88-9 |
Nomoro ea KAtse | RF-API59 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C51H79NO13 |
Boima ba Molek'hule | 914.19 |
Melting Point | 183.0 ~ 185.0 ℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu |
Boitsebiso A | The IR spectrum ea potassium bromide e lokisoang ea sampole e bonts'a maxima ka bolelele bo ts'oanang le ba boitokiso bo ts'oanang ba litekanyetso tsa litšupiso tsa ka tlung. |
Boitsebiso B | Maqhubu a UV a 95% ea ho lokisoa ha ethanol ea sampole e bonts'a boholo ba 267nm, 277nm, 288nm joalo ka boitokiso bo ts'oanang ba litekanyetso tsa litšupiso tsa ka tlung. |
Boitsebiso C | Nako ea ho boloka litlhoro tsa trans-le cis-stereoisomers ho chromatogram ea assay preparation e tsamaellana le e ho chromatogram ea tokiso e tloaelehileng, joalo ka ha e fumanoe tlhahlobong. |
Ho potoloha ha Optical | -147.0°~ -157.0° |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.20% |
Litšepe tse boima | ≤20ppm |
Tšilafalo ea Motho ka Mong | ≤1.5% |
Litšila ka Kakaretso | ≤2.0% (ntle le Cis-Stereoisomer ea Sirolimus) |
Cis-Stereoisomer ea Sirolimus | ≤5.0% |
Metsoako e setseng | |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
Diethyl Ether | ≤5000ppm |
Tlhahlobo | ≥98.5% (Ho baloa trans- le cis-stereoisomer ea sirolimus ho latela maemo a sa tsitsang) |
Tekanyetso ea Teko | Pharmacopoeia ea Chaena (CP);Maemo a Khoebo |
Tšebeliso | Active Pharmaceutical ingredient (API) |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Rapamycin (Sirolimus; AY 22989) ke autophagy activator, mofuta o mocha oa macrolide immunosuppressive agent e nang le litlamorao tse ntle tsa kalafo, chefo e tlase, 'me ha e na nephrotoxicity.E ka sebelisoa ho boloka ts'ireletso ea 'mele oa litho tsa transplant (haholo-holo ho transplants ea liphio) ho fokotsa ho lahloa ha sesole sa 'mele ka mor'a opereishene ea ho fetisetsa setho.