Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

Tlhaloso e Khutšoanyane:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

CAS: 1354823-36-1

Bohareng ba Remdesivir (CAS 1809249-37-3) bakeng sa kalafo ea COVID-19

Boleng bo Phahameng, Tlhahiso ea Khoebo

Inquiry: alvin@ruifuchem.com

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Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Remdesivir ea Phepelo ea Khoebo le Litšehare tse Amanang le Boleng bo Phahameng
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2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
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Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester
Litlhaloso tse tšoanang	Remdesivir ea Mahareng;Remdesivir Side Chain;Remdesivir p-NitroPhenoxy L-Alanine Tšilafalo;Remdesivir Ho se hloeke 4;Remdesivir-002;(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate
Nomoro ea CAS	1354823-36-1
Nomoro ea KAtse	RF-PI297
Boemo ba Setoko	Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma
Foromo ea limolek'hule	C21H27N2O7P
Boima ba Molek'hule	450.42
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Bosoeu ho isa ho e Batlileng e Tsweu
Boitsebiso	IR, HPLC
Tahlehelo ka ho Omisa	≤1.0%
Tšilafalo e le Mong	≤0.50%
Litšepe tse boima	≤20ppm
Bohloeki	≥98.0%
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Remdesivir (CAS 1809249-37-3);COVID 19

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

LBH:

Kopo:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, e tsejoang hape e le Remdesivir Impurity 4) ke phosphoramidate sidechain e atisang ho sebelisoa bakeng sa ho lokisa Remdesivir (CAS . 1809249-37-3, GS-5734), e leng sethethefatsi sa lipatlisiso sa antiviral qalong bakeng sa kalafo ea lefu la Ebola virus le tšoaetso ea kokoana-hloko ea Marburg 'me hamorao e fumanoe e bontša ts'ebetso ea antiviral khahlano le coronavirus (mohlala, SARS-Cov-2 / Covid 19).Nakong ea ho qhoma ha Lefu le lecha la Coronavirus 2019 (COVID-19), Remdesivir (CAS 1809249-37-3) ke e 'ngoe ea lihlahisoa tsa lipatlisiso tse amanang le COVID-19.Remdesivir, e rekisoang ka lebitso la Veklury, ke moriana o thibelang likokoana-hloko o pharalletseng o entsoeng ke k'hamphani ea biopharmaceutical Gilead Sciences.E tsamaisoa ka ente ka har'a mothapo.Nakong ea seoa sa COVID-19, Remdesivir e ile ea amoheloa kapa ea lumelloa bakeng sa tšebeliso ea tšohanyetso ho phekola COVID-19 linaheng tse ka bang 50.Litaelo tse ntlafalitsoeng ho tsoa ho Mokhatlo oa Lefatše oa Bophelo ka Pulungoana 2020 li kenyelletsa khothaletso e nang le maemo khahlano le ts'ebeliso ea Remdesivir bakeng sa kalafo ea COVID-19.