Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

CAS: 1911578-98-7

Ponahalo: Phofo e tšoeu ho isa ho e tšoeuBohloeki: ≥98.0%

Bohareng ba Remdesivir (CAS 1809249-37-3) COVID-19

Boleng bo Phahameng, Tlhahiso ea Khoebo

Inquiry: alvin@ruifuchem.com

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Tlhaloso:

Remdesivir ea Phepelo ea Khoebo le Litšehare tse Amanang le Boleng bo Phahameng
Remdesivir CAS 1809249-37-3
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2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
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Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
Litlhaloso tse tšoanang	N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester;Remdesivir ea Mahareng;Remdesivir-001;Tšilafalo ea Remdesivir 21
Nomoro ea CAS	1911578-98-7
Nomoro ea KAtse	RF-PI303
Boemo ba Setoko	Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma
Foromo ea limolek'hule	C21H27N2O7P
Boima ba Molek'hule	495.38
Botenya	1.2g/cm3
Melting Point	92.0~96.0℃(lit.)
Ntlha e belang	356.7 ℃ ho 760 mmHg
Boemo ba ho Romela	E Rometsoe ka Tlas'a Mocheso oa Mocheso
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e tšoeu ho isa ho e tšoeu
Infrared Spectrum	E Ikamahanya le Sebopeho
Bohloeki	≥99.0%
Tahlehelo ka ho Omisa	≤0.50%
Tšilafalo e le Mong	≤0.50%
Litšila ka Kakaretso	≤1.0%
Litšepe tse boima	≤20ppm
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Remdesivir (CAS 1809249-37-3)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

LBH:

Kopo:

2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) ke senotlolo se tsoetseng pele ha ho lokisoa li-analogue tse amanang le Remdesivir.Remdesivir ke monophosphoramidate prodrug ea analog ea adenosine, ke sesebelisoa sa lipatlisiso se pharaletseng se nang le ts'ebetso ea in vitro khahlano le SARS coronavirus, MERS coronavirus le, haufinyane tjena, Covid-19.Remdesivir e ntlafalitsoe haholo e le kalafo ea tšoaetso ea filovirus joalo ka lefu la vaerase ea Ebola kapa vaerase ea Marburg.Kamora moo, Remdesivir e ile ea fumanoa e bonts'a ts'ebetso ea antiviral khahlano le livaerase tse ling tsa RNA tse nang le mela e le 'ngoe joalo ka vaerase ea syncytial ea ho hema, vaerase ea Nipah, vaerase ea Hendra, vaerase ea Junin, vaerase ea Lassa fever le coronaviruses (ho kenyeletsoa livaerase tsa MERS le SARS).Haufinyane tjena e ntse e ithutoa joalo ka moriana o ts'episang bakeng sa kalafo ea COVID-19 (vaerase e ncha ea mofuta oa SARS).Remdesivir, e ntlafalitsoeng ke Saense ea Gileade, ke sehlahisoa sa adenosine se kenellang ka har'a sebopeho sa sona se sebetsang GS-441524 se sitisang ketso ea RNA polymerase e itšetlehileng ka vaerase ea RNA mme e qoba ho hlahloba liphoso ka vaerase exoribonuclease (ExoN), e bakang phokotso ea tlhahiso ea RNA ea vaerase.