(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate Factory

Tlhaloso e Khutšoanyane:

Lebitso la Lik'hemik'hale: (S) -1,2,3,4-1-Tetrahydro-Naphthoic Acid

CAS: 85977-52-2

Ponahalo: Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu

Bohloeki: ≥99.0%

Enantimoer Excess: ee≥99.0%

Bohareng ba Palonosetron Hydrochloride (CAS: 135729-62-3) kalafo ea CINV

E-mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Phepelo ea Khoebo Palonosetron Hydrochloride le Li-intermediate tse Amanang:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S) -3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid
Litlhaloso tse tšoanang	(1S) -1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid
Nomoro ea CAS	85977-52-2
Nomoro ea KAtse	RF-CC111
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C11H12O2
Boima ba Molek'hule	176.21
Botenya	1.186g/cm3
Melting Point	54.0 ~ 56.0℃
Ntlha e belang	342.7°C ho 760 mmHg
Refractive Index	1.576
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu
Bohloeki ba Lik'hemik'hale	≥99.0%
Enantimoer Fetello	ee ≥99.0%
Tšilafalo ea Isomer	≤1.0%
Tahlehelo ka ho Omisa	≤0.50%
Amahanya Ntho	≤1.0%
Mongobo (KF)	≤1.0%
Potoloho e Khethehileng [α]_D²⁰	-59.0°~ -63.0°(C=0.3 ho Benzence)
Litšepe tse boima	≤20ppm
Polokelo	5-8 ℃ Ho thibela moea
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Palonosetron Hydrochloride (CAS: 135729-62-3) Bohareng

(S) -1,2,3,4-tetrahydro-1-Naphthoic Acid CAS: 85977-52-2 Route of Synthesis

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Moqomo oa Cardboard, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

LBH:

Kopo:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa (S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) e nang le boleng bo phahameng.Ke karolo e bohareng ka tloaelo ho motsoako oa Palonosetron Hydrochloride (CAS: 135729-62-3).

Palonosetron Hydrochloride (CAS: 135729-62-3) ke mohanyetsi oa li-receptor tsa 5-HT3 tse qalileng e le moemeli ea nang le ente bakeng sa ho thibela ho nyekeloa ke pelo ho hoholo le ho lieha le ho hlatsa tse amanang le chemotherapy ea mofetše.E na le nako e telele haholo ea halofo ea bophelo (~ 40 h) ho feta bahanyetsi ba bang ba 5-HT3 ba teng hona joale, e fanang ka melemo ea katleho ho thibela ho lieha ho nyekeloa ke pelo le ho hlatsa hoo hangata ho hlahang ka mor'a 24 h le ho fihlela matsatsi a tšeletseng a tsamaiso ea chemotherapy.Ka 1,2,3,4-tetrahydro-1-Naphthoic Acid e le thepa ea ho qala, ho arohana, ho fokotsa, ho fokotsa, cyclization, letsoai la palonosetron hydrochloride granisetron.