(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Purity ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate Factory
Phepelo ea Khoebo Palonosetron Hydrochloride le Li-intermediate tse Amanang:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S) -3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
Lebitso la Lik'hemik'hale | (S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid |
Litlhaloso tse tšoanang | (1S) -1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid |
Nomoro ea CAS | 85977-52-2 |
Nomoro ea KAtse | RF-CC111 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C11H12O2 |
Boima ba Molek'hule | 176.21 |
Botenya | 1.186g/cm3 |
Melting Point | 54.0 ~ 56.0℃ |
Ntlha e belang | 342.7°C ho 760 mmHg |
Refractive Index | 1.576 |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu |
Bohloeki ba Lik'hemik'hale | ≥99.0% |
Enantimoer Fetello | ee ≥99.0% |
Tšilafalo ea Isomer | ≤1.0% |
Tahlehelo ka ho Omisa | ≤0.50% |
Amahanya Ntho | ≤1.0% |
Mongobo (KF) | ≤1.0% |
Potoloho e Khethehileng [α]D20 | -59.0°~ -63.0°(C=0.3 ho Benzence) |
Litšepe tse boima | ≤20ppm |
Polokelo | 5-8 ℃ Ho thibela moea |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Palonosetron Hydrochloride (CAS: 135729-62-3) Bohareng |
(S) -1,2,3,4-tetrahydro-1-Naphthoic Acid CAS: 85977-52-2 Route of Synthesis
Sephutheloana: Botlolo, Moqomo oa Cardboard, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
![1](https://a395.goodao.net/uploads/15.jpg)
![2](https://a395.goodao.net/uploads/23.jpg)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa (S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) e nang le boleng bo phahameng.Ke karolo e bohareng ka tloaelo ho motsoako oa Palonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) ke mohanyetsi oa li-receptor tsa 5-HT3 tse qalileng e le moemeli ea nang le ente bakeng sa ho thibela ho nyekeloa ke pelo ho hoholo le ho lieha le ho hlatsa tse amanang le chemotherapy ea mofetše.E na le nako e telele haholo ea halofo ea bophelo (~ 40 h) ho feta bahanyetsi ba bang ba 5-HT3 ba teng hona joale, e fanang ka melemo ea katleho ho thibela ho lieha ho nyekeloa ke pelo le ho hlatsa hoo hangata ho hlahang ka mor'a 24 h le ho fihlela matsatsi a tšeletseng a tsamaiso ea chemotherapy.Ka 1,2,3,4-tetrahydro-1-Naphthoic Acid e le thepa ea ho qala, ho arohana, ho fokotsa, ho fokotsa, cyclization, letsoai la palonosetron hydrochloride granisetron.
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