(S) -3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Bohloeki ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate
Phepelo ea Khoebo Palonosetron Hydrochloride le Li-intermediate tse Amanang:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S) -3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Lebitso la Lik'hemik'hale | (S) -3-Aminoquinuclidine Dihydrochloride |
| Litlhaloso tse tšoanang | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Nomoro ea CAS | 119904-90-4 |
| Nomoro ea KAtse | RF-CC112 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C7H16Cl2N2 |
| Boima ba Molek'hule | 199.12 |
| Botenya | 1.24g/cm3 |
| Melting Point | 260 ℃ |
| Ntlha e belang | 470.4 ℃ ho 760mmHg |
| Sollubility ka Metsing | E qhibilihang |
| Boemo ba ho Romela | E Rometsoe ka Tlas'a Mocheso oa Mocheso |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e Bosoeu ho ea ho Khanyang |
| IR | Absorption Spectra e tsamaellanang le Reference |
| Karabelo ea Chloride | Karabelo e Ntle |
| Purity (HPLC) | ≥98.0% |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Potoloho e Khethehileng [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Litšepe tse boima | ≤20ppm |
| Polokelo | 5-8 ℃ Ho thibela moea |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Palonosetron Hydrochloride (CAS: 135729-62-3) Bohareng |
(S) -3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Tsela ea Synthetic
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) e nang le boleng bo phahameng.Ke motsoako oa meriana ka tloaelo ho motsoako oa Palonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) ke lithethefatsi tse thibelang ho nyekeloa ke pelo le ho hlatsa, e leng mofuta o mocha o khethang haholo, o nang le kamano e phahameng ea 5-HT3 receptor mohanyetsi o ka thibelang ho hlatsa reflex center peripheral neurons presynaptic 5-HT.Thabo ea moamoheli e ama ka kotloloho tsamaiso ea methapo e bohareng ho 5-HT.Thabo ea receptor ea impulse e hlahisoang ke karolo ea vagal afferent nerve ka mor'a sebaka, ho thibela lipheletsong tsa methapo ea vagus ka maleng, ho thibela lipontšo ho 5-HT.Receptor trigger zone e ka fokotsa sekhahla sa ho nyekeloa ke pelo le ho hlatsa.Bohareng ba bongaka bakeng sa kalafo ea chemotherapy e matla haholo ea emetogenic e bakileng ho nyekeloa ke pelo le ho hlatsa ho lieha.Ka lebaka la phello ea eona e phahameng ea ho folisa, phello e fokolang ea lehlakore, nako e telele ea halofo ea bophelo (hoo e ka bang 40 h), tekanyo e nyane, joalo-joalo, e hohetse tlhokomelo e ngata.Ka 1,2,3,4-tetrahydro-1-naphthoic acid e le thepa ea ho qala, ho arohana, ho fokotsa, ho fokotsa, cyclization, letsoai la palonosetron hydrochloride granisetron.Liphuputso tsa bongaka li bontšitse hore palonosetron e ka sebelisoa ka mokhoa o sireletsehileng ka corticosteroids, analgesics, antiemetics, antispasmodics le anticholinergic lithethefatsi joaloka lisebelisoa tsa ho qala, ho arohana, ho fokotsa, ho fokotsa, cyclization, letsoai la palonosetron hydrochloride granisetron.
