Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Purity >99.0% (HPLC) API Factory High Quality
Fana ka Sitagliptin Phosphate Monohydrate tse Amanang le Mekhatlo:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Ea Hare CAS 486460-21-3
| Lebitso la Lik'hemik'hale | Sitagliptin Phosphate Monohydrate |
| Litlhaloso tse tšoanang | (R) -3-amino-1-(3-(trifluoromethyl) -5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4- (2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate |
| Nomoro ea CAS | 654671-77-9 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | Setšoantšo sa C16H20F6N5O6P |
| Boima ba Molek'hule | 523.3240802 |
| Melting Point | 202.0~204.0℃ |
| Ho qhibiliha ha Metsi | E qhibilihang ka Metsing |
| Phetoho e khethehileng | -18.0°~-23.0° (C=1, Metsi) |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
| Boitsebiso ka HPLC | Nako ea ho boloka sampole e lumellana le maemo a referense |
| IR-Infrared Spectrum | IR Absorption Spectrum ea sampole e tla lumellana le ea spectrum e tloaelehileng |
| Phosphate | E lumellana |
| Mokhoa oa Bohloeki / Analysis | > 99.0% (HPLC motheong o omisitsoeng) |
| Litaba tsa Metsi (KF) | 3.3%~4.4% |
| Masalla a ho Ignition | ≤0.20% |
| Sulfate | ≤0.02% |
| Chloride | ≤0.05% |
| Tšilafalo ea Chiral | <0.50% |
| Lintho Tse Amanang | |
| Tšilafalo e le Mong | <0.50% |
| Litšila ka Kakaretso | <1.0% |
| Ethyl Acetate | <0.50% |
| Litšepe tse boima | <20ppm |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Mekhatlo ea Meriana |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9), sethethefatsi se secha sa kalafo ea lefu la tsoekere la mofuta oa 2.Ka Phato 2009, moriana ona o ile oa amoheloa ke European Union e le moriana oa pele oa kalafo ea lefu la tsoekere la mofuta oa 2.Sitagliptin Phosphate ke inhibitor ea pele e amohetsoeng ke FDA ea dipeptidyl peptidase-IV e sebelisoang ho phekola lefu la tsoekere la mofuta oa 2 ho fihlela joale, tlasa lebitso la khoebo la Januvia.Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) e theola kapele le ka nepo GLP-1, GLP-1, e leng se susumetsang haholo tlhahiso le secretion ea insulin Ka hona, ho thibela DPP-IV ho ka ntlafatsa karolo ea endogenous GLP-1, ka hona, mali a eketseha. insulin, ka hona, e fokotsa le ho boloka boemo ba tsoekere ea mali ho bakuli ba nang le lefu la tsoekere.Hona joale, meriana e netefalitse hore DPP-IV inhibitor ke mofuta o mocha oa lithethefatsi tse khahlanong le lefu la tsoekere, 'me liphello tsa kliniki li bontša hore lithethefatsi li na le phello e ntle ea hypoglycemic.Kaha GLP-1 e na le karolo e itšetlehileng ka tsoekere ho nts'etsopele le tlhahiso ea insulin, litlamorao tse tloaelehileng tse joalo ka hypoglycemia le boima ba 'mele bo bakoang ke ts'ebeliso ea lithethefatsi tsa antidiabetes ha li hlahe.
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