Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API Factory High Quality
Phepelo ea Khoebo Sorafenib Tosylate le Li-Intermediate tse Amanang:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
| Lebitso | Sorafenib |
| Litlhaloso tse tšoanang | Sorafenib Free Base |
| Nomoro ea CAS | 284461-73-0 |
| Nomoro ea KAtse | RF-API04 |
| Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
| Foromo ea limolek'hule | C21H16ClF3N4O3 |
| Boima ba Molek'hule | 464.82 |
| Botenya | 1.454±0.06 g/cm3 |
| Solubility | E qhibiliha ka DMSO |
| Maemo a ho Romela | Ambient Mocheso |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu |
| Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) |
| Boitsebiso | H-NMR, MS |
| Tahlehelo ka ho Omisa | ≤1.0% |
| Masalla a ho Ignition | ≤0.10% |
| Tšilafalo e le Mong | ≤0.20% (HPLC) |
| Litšila ka Kakaretso | ≤1.0% (HPLC) |
| Litšepe tse boima | ≤20ppm |
| Ho Hlakola ha Tharollo | Ikamahanye le Maemo |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | RCC & HCC |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Sorafenib Tosylate (CAS: 475207-59-1) ke mofuta o mocha oa lithethefatsi tse thibelang likokoana-hloko tse ngata, tse entsoeng ke Jeremane Bayer Pharmaceuticals, 'me li bonts'a ts'ebetso e matla ea antitumor litekong tsa pele tsa liphoofolo.Sorafenib e fumaneha ka matlapa a 200-mg bakeng sa tsamaiso ea molomo 'me e sebelisoa ho phekola RCC le HCC.Sorafenib Tosylate (CAS: 475207-59-1) e ka ama ka nako e le 'ngoe lisele tsa tumor le methapo ea mali ea tumor.E na le phello e 'meli ea antitumor: e ka thibela litsela tsa phetisetso ea lisele tse kentsoeng ke RAF / MEK / ERK ho thibela ka ho toba ho hōla ha lisele tsa tumor, ha e ntse e thibela VEGF le platelet derived growth factor (PDGF) ho thibela ho thehoa ha mali a macha. lijana, kahoo ka tsela e sa tobang thibela ho hōla ha lisele tsa hlahala.Sorafenib ke inhibitor ea Raf-1 le B-RAF hammoho le li-tyrosine kinase tse 'maloa.
