Tacrolimus FK-506 Fujimycin CAS 104987-11-3 API Factory High Purity

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Tacrolimus

Mantsoe a tšoanang: FK-506;Fujimycin

CAS: 104987-11-3

Ponahalo: Phofo e Ntle-Bosoeu kapa Bosehla bo Bosehla, E sa nkhang hamonate, Tatso e Khethehileng e Monate

Assay: ≥72.0% (HPLC, motheong o omisitsoeng)

API, Boleng bo Phahameng, Tlhahiso ea Khoebo

E-mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Moetsi ea nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Tacrolimus
Mantsoe a tšoanang: FK-506;Fujimycin
CAS: 104987-11-3
API, Boleng bo Phahameng, Tlhahiso ea Khoebo

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Tacrolimus
Litlhaloso tse tšoanang	FK-506;Fujimycin
Nomoro ea CAS	104987-11-3
Nomoro ea KAtse	RF-API46
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C44H69NO12
Boima ba Molek'hule	804.02
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Ntle-Bosoeu kapa Bosehla bo Bosehla, Ha e Monko, Tatso e Ikgethileng e Monate
Boitsebiso	E Lokela ho ba Karabelo e Ntle
Ho hlaka	Ikamahanye le Maemo
pH	5.0~6.0
Chloride	≤0.014%
Sulfate	≤0.029%
Litšepe tse boima (Pb)	≤10ppm
Arsenic	≤0.0002%
Mongobo (KF)	≤8.0%
Masalla a ho Ignition	18.0%~22.0%
Tlhahlobo	≥72.0% (HPLC, motheong o omisitsoeng)
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	API

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

LBH:

Kopo:

Tacrolimus (hape FK-506 kapa Fujimycin) ke lithethefatsi tse thibelang ho itšireletsa mafung tseo tšebeliso ea tsona e ka sehloohong e leng ka mor'a ho kenya setho sa 'mele ho fokotsa ts'ebetso ea tsamaiso ea' mele ea ho itšireletsa mafung 'me kahoo kotsi ea ho hana litho tsa' mele.E boetse e sebelisoa ka topical topical a kalafo ea matla atopic dermatitis, matla refractory uveitis ka mor'a hore lesapo transplants, le letlalo boemo vitiligo.Tacrolimus e ile ea ntšoa ka lekhetlo la pele morong o belisoang oa Streptomyces tssukuba, kokoana-hloko ea mobu e fumanoang Tsukuba, Japane.Lebitso tacrolimus le nkiloe ka ho nka 't' bakeng sa Tsukuba, lebitso la thaba moo sampole ea mobu e ntšitsoeng teng, 'acrol' bakeng sa macrolide le 'imus' bakeng sa immunosuppressant.Le hoja e sa amane le cyclosporin, tacrolimus e bontša palo e tšoanang ea liphello tsa immunosuppressive ho moemeli enoa boemong ba lisele le limolek'hule.Liphuputso tsa pele li bonts'itse hore tacrolimus e ne e le immunosuppressant e matla, e bonts'ang matla a in vitro ka makhetlo a ka bang 100 ho feta cyclosporin ho thibela ts'ebetso ea T cell.Liphuputso tse latelang tsa vivo li bonts'itse tacrolimus e sebetsa ka bobeli ho hatelleng lefu le itlhahisang le litekong tsa autoimmune, le ho thibela ho hana allograft le xenograft mefuteng ea liphoofolo ea phetisetso ea setho.Qalong, tacrolimus e ne e sebelisoa bakeng sa tsamaiso ea 'mele ea ho itšireletsa mafung ea bakuli ba neng ba e-na le li-transplant tsa allograft ho ba thibela ho hana li-graft tsa bona tse ncha.Leha ho le joalo, haufinyane, ka molemo oa serendipity ea saense, ho ile ha hlokomeloa hore tacrolimus e ka hlahisa liphello tse ntle ho mafu a letlalo ho ba bang ba bakuli ba neng ba e-na le transplantation.Ho sibolloa ha tacrolimus ka hona ho lebisitse kutloisisong e kholo ea lefu la letlalo, mohlala oa atopic dermatitis.Kamora moo, lits'ebetso tse ling tsa topical tsa tacrolimus li ile tsa tlalehoa mme ts'ebeliso ea moemeli ona ho dermatology e ntse e hola butle.