Telmisartan CAS 144701-48-4 Bohloeki >99.5% (HPLC) API Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Telmisartan

CAS: 144701-48-4

Bohloeki: >99.5% (HPLC)

Ponahalo: Crystalline e tšoeu kapa e sa bosoeu

Angiotensin II Receptor Antagonist

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale Telmisartan
Litlhaloso tse tšoanang 4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol] -1'-yl)methyl]-[1,1'-Biphenyl] -2-Carboxylic Acid
Nomoro ea CAS 144701-48-4
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule C33H30N4O2
Boima ba Molek'hule 514.63
Melting Point 261.0~263.0℃
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Phofo ea Crystalline e tšoeu kapa e sa Tšoeu
Monko o monate Sebopeho
Solubility E qhibiliha hanyenyane ka methylene Chloride, e Hanyenyane ha e Souble ka Methanol, Parctically Insoluble ka Metsing, E qhibiliha ka 1M Solution Hydroxide
Boitsebiso ba IR E Lokela ho Kopana le RS Infrared Absorption
Boitsebiso ba HPLC Nako ea ho Boloka Peak e Khōlō e Lokela ho Kopana le RS
Mokhoa oa Bohloeki / Analysis >99.5% (HPLC)
Tahlehelo ka ho Omisa <1.00%
Masalla a ho Ignition <0.10%
Lintho Tse Amanang  
Motsoako o amanang le Telmisartan A <0.10%
Telmisartan Amide <0.10%
Telmisartan e amanang le Motsoako oa B <0.10%
Telmisartan Diacide <0.10%
Telmisartan Tert-Butyl Ester <0.20%
Tšilafalo e sa Tsejoeng ea Telmisartan <0.20%
Tšilafalo e sa Boleloeng <0.10%
Litšila ka Kakaretso <1.00%
Metsoako e setseng  
Methanol <0.30%
Ethanol <0.50%
Methylene dichloride <0.06%
n-Hexane <0.029%
Acetic Acid Ethyl Ester <0.50%
Toluene <0.089%
Acetic Acid <0.50%
Litšepe tse boima <10ppm
Arsenic (As) <1.00ppm
Ketapele (Pb) <1.00ppm
Cadmium (Cd) <1.00ppm
Boholo ba Karolo D90 Ha e Feta 15μm
Boima ba Bongata (g/cc) 0.11~0.20
Boima ba Matla (g/cc) 0.22 ~ 0.30
Sebolaea Likokoanyana se Seng E mpe
Kakaretso ea Plate Count <1000cfu/g
Yeast & Mold <100cfu/g
E. Coli E mpe
Salmonella E mpe
Tekanyetso ea Teko Maemo a Khoebo;USP 41 E tloaelehileng
Tšebeliso API

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

1

LBH:

Kopo:

Telmisartan (CAS: 144701-48-4) ke ntho e nkiloeng ho benzimidazole le mohanyetsi oa li-receptor tsa angiotensin II tseo e seng tsa peptide tse nang le thepa ea antihypertensive.Telmisartan ka boikhethelo e hanyetsana le angiotensin II e tlamang ho li-receptor tsa mofuta oa AT1, tse ka har'a mesifa e boreleli ea methapo le tšoelesa ea adrenal.Bohanyetsi bo fella ka vasodilation le ho thibela tlhahiso ea aldosterone ea angiotensin II, e leng eona e lebisang ho fokotseha ha sodium le metsi hammoho le ho eketseha ha potasiamo e hlahisang phokotso e latelang ea khatello ea mali.Telmisartan ke mofuta o mocha oa lithethefatsi tsa khatello ea mali, o sebelisoa o le mong kapa o kopantsoe le lihlopha tse ling tsa antihypertensive bakeng sa kalafo ea khatello ea mali.Telmisartan qalong e ne e entsoe ke k'hamphani ea meriana ea Jeremane Boehringer Ingelheim;e ile ea fumana tokelo ea molao ea Jeremane EP502,314 ka 1991, e ile ea amoheloa ka lekhetlo la pele hore e kene 'marakeng oa Amerika ka Pulungoana 1998, eaba ea kena limmarakeng tsa Jeremane, Philippines, Australia, Belgium, Brithani le tse ling.

Ngola molaetsa wa hao mona mme o re romele wona