Telmisartan CAS 144701-48-4 Bohloeki >99.5% (HPLC) API Factory
Phepelo ea Lik'hemik'hale ea Ruifu Telmisartan e Kena ka Bohloeki bo Phahameng
Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl)benzoic Acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9
Lebitso la Lik'hemik'hale | Telmisartan |
Litlhaloso tse tšoanang | 4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol] -1'-yl)methyl]-[1,1'-Biphenyl] -2-Carboxylic Acid |
Nomoro ea CAS | 144701-48-4 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C33H30N4O2 |
Boima ba Molek'hule | 514.63 |
Melting Point | 261.0~263.0℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu |
Monko o monate | Sebopeho |
Solubility | E qhibiliha hanyenyane ka methylene Chloride, e Hanyenyane ha e Souble ka Methanol, Parctically Insoluble ka Metsing, E qhibiliha ka 1M Solution Hydroxide |
Boitsebiso ba IR | E Lokela ho Kopana le RS Infrared Absorption |
Boitsebiso ba HPLC | Nako ea ho Boloka Peak e Khōlō e Lokela ho Kopana le RS |
Mokhoa oa Bohloeki / Analysis | >99.5% (HPLC) |
Tahlehelo ka ho Omisa | <1.00% |
Masalla a ho Ignition | <0.10% |
Lintho Tse Amanang | |
Motsoako o amanang le Telmisartan A | <0.10% |
Telmisartan Amide | <0.10% |
Telmisartan e amanang le Motsoako oa B | <0.10% |
Telmisartan Diacide | <0.10% |
Telmisartan Tert-Butyl Ester | <0.20% |
Tšilafalo e sa Tsejoeng ea Telmisartan | <0.20% |
Tšilafalo e sa Boleloeng | <0.10% |
Litšila ka Kakaretso | <1.00% |
Metsoako e setseng | |
Methanol | <0.30% |
Ethanol | <0.50% |
Methylene dichloride | <0.06% |
n-Hexane | <0.029% |
Acetic Acid Ethyl Ester | <0.50% |
Toluene | <0.089% |
Acetic Acid | <0.50% |
Litšepe tse boima | <10ppm |
Arsenic (As) | <1.00ppm |
Ketapele (Pb) | <1.00ppm |
Cadmium (Cd) | <1.00ppm |
Boholo ba Karolo | D90 Ha e Feta 15μm |
Boima ba Bongata (g/cc) | 0.11~0.20 |
Boima ba Matla (g/cc) | 0.22 ~ 0.30 |
Sebolaea Likokoanyana se Seng | E mpe |
Kakaretso ea Plate Count | <1000cfu/g |
Yeast & Mold | <100cfu/g |
E. Coli | E mpe |
Salmonella | E mpe |
Tekanyetso ea Teko | Maemo a Khoebo;USP 41 E tloaelehileng |
Tšebeliso | API |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Telmisartan (CAS: 144701-48-4) ke ntho e nkiloeng ho benzimidazole le mohanyetsi oa li-receptor tsa angiotensin II tseo e seng tsa peptide tse nang le thepa ea antihypertensive.Telmisartan ka boikhethelo e hanyetsana le angiotensin II e tlamang ho li-receptor tsa mofuta oa AT1, tse ka har'a mesifa e boreleli ea methapo le tšoelesa ea adrenal.Bohanyetsi bo fella ka vasodilation le ho thibela tlhahiso ea aldosterone ea angiotensin II, e leng eona e lebisang ho fokotseha ha sodium le metsi hammoho le ho eketseha ha potasiamo e hlahisang phokotso e latelang ea khatello ea mali.Telmisartan ke mofuta o mocha oa lithethefatsi tsa khatello ea mali, o sebelisoa o le mong kapa o kopantsoe le lihlopha tse ling tsa antihypertensive bakeng sa kalafo ea khatello ea mali.Telmisartan qalong e ne e entsoe ke k'hamphani ea meriana ea Jeremane Boehringer Ingelheim;e ile ea fumana tokelo ea molao ea Jeremane EP502,314 ka 1991, e ile ea amoheloa ka lekhetlo la pele hore e kene 'marakeng oa Amerika ka Pulungoana 1998, eaba ea kena limmarakeng tsa Jeremane, Philippines, Australia, Belgium, Brithani le tse ling.