Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Purity
Fana ka Temozolomide le li-Intermediate tse Amanang:
Temozolomide CAS: 85622-93-1
4(5)-Amino-5(4)-Imidazolecarboxamide CAS: 360-97-4
5(4)-Amino-4(5)-Imidazolecarboxamide Hydrochloride CAS: 72-40-2
| Lebitso la Lik'hemik'hale | Temozolomide |
| Litlhaloso tse tšoanang | 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-Carboxamide |
| Nomoro ea CAS | 85622-93-1 |
| Nomoro ea KAtse | RF-API29 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C6H6N6O2 |
| Boima ba Molek'hule | 194.15 |
| Melting Point | 212 ℃ dec. |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e Bosoeu ho isa ho Bopinki bo Khanyang |
| Boitsebiso | Ka IR, HPLC |
| Metsoako e setseng | Dimethyl Sulphoxide ≤0.50% |
| Lintho Tse Amanang | |
| Ho se hloeke AIC | ≤0.10% |
| Tšilafalo e le Mong | ≤0.10% |
| Phomola Litšila Tse sa Tsejoeng | ≤0.30% |
| Litšila ka Kakaretso | ≤0.30% |
| Litšepe tse boima | ≤10ppm |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Masalla a ho Ignition | ≤0.10% |
| Tlhahlobo | 99.0% ~ 101.0% (HPLC motheong o omisitsoeng) |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Active Pharmaceutical ingredient (API) |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Temozolomide (CAS: 85622-93-1) e nang le boleng bo phahameng.Temozolomide (TMZ) ke moemeli oa alkylating oa molomo o sebelisetsoang ho phekola Glioblastoma Multiforme (GBM) le Astrocytomas, Metastatic Melanoma.
Temozolomide ke moriana oa pele o sebetsang ka molomo oa imidazole le tetrazine-class anticancer e leng oa moloko oa bobeli oa alkylating agent e nang le ts'ebetso ea antitumor ntle le ts'ebetso ea sebete ea metabolism ka mor'a tsamaiso ea molomo.E tšoauoa ka ho kenella habonolo ka mokoallo oa mali-bokong, mamello e ntle le ho se be le chefo ea lithethefatsi tse ling, 'me e na le phello ea synergistic le radiotherapy e loketseng ho phekola ho khutla ha glioma ka mor'a phekolo e tloaelehileng e kang glioblastoma multiforme tumors kapa degenerative astrocytoma.Ke sethethefatsi sa pele sa ho phekola melanoma ea metastatic.
Temozolomide e ne e entsoe ka lekhetlo la pele ke Cancer Research UK Group, ebe e fetisetsoa ho Khamphani ea Schering-Plough (United States) bakeng sa nts'etsopele.E na le sebopeho se secha sa lik'hemik'hale 'me ke sa motsoako oa imidazole tse' nè.Ka 1999, e amohetsoe hore e kene 'marakeng ho EU le US moo letšoao le lumelletsoeng United States e leng la mofuta oa bobeli oa kalafo ea glioblastoma multiforme le degenerative star gliomas le matšoao a amohetsoeng a EU ke ho phekola ho nts'etsapele kapa ho khutlisa glioblastoma multiforme. e seng e le tlasa kalafo e tlwaelehileng.Ho sebetsa hantle ha temozolomide ho alafeng glioblastoma multiforme ho fumane tlhokomelo e eketsehileng Europe.
