tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Purity >98.0% (HPLC) Palbociclib Intermediate Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate

Mantsoe a tšoanang: 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine

CAS: 571189-16-7

Bohloeki: >98.0% (HPLC)

Ponahalo: Bosootho bo Khanyang ho ea ho Phofo e Sootho

Bohareng ba Palbociclib (CAS: 571190-30-2)

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate
Litlhaloso tse tšoanang	1-Boc-4-(6-Nitro-3-Pyridyl)piperazine;4-(6-Nitro-3-pyridinyl) -1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate
Nomoro ea CAS	571189-16-7
Nomoro ea KAtse	RF-PI1850
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	Setšoantšo sa C14H20N4O4
Boima ba Molek'hule	308.33
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Bosootho bo bobebe ho isa ho phofo e sootho
Mokhoa oa Bohloeki / Analysis	>98.0% (HPLC)
LCMS	E Lumellanang le Sebopeho
Tahlehelo ka ho Omisa	<1.00%
Litšila ka Kakaretso	<2.00%
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Palbociclib (CAS: 571190-30-2)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS: 571189-16-7) ke karolo e bohareng ea Palbociclib (CAS: 571190-30-2).Palbociclib (eo hape e tsejoang e le nomoro ea komporo PD-0332991) ke setlhare sa liteko bakeng sa kalafo ea mofetše oa matsoele o hlahisoang ke Pfizer.Ke inhibitor e khethiloeng ea CDK4 le CDK6 e itšetlehileng ka li-cyclin.Palbociclib e thibela tsoelo-pele ea potoloho ea lisele ho tloha karolong ea G1 ho ea ho S ka ho thibela CDK4/6-e itšetlehileng ka retinoblastoma (RB) phosphorylation.Palbociclibhas e 'nile ea sebelisoa bakeng sa phekolo ea HER2 negative, estrogen receptor (ER) e ntle ea kankere ea matsoele ea metastatic.