Tolvaptan CAS 150683-30-0 API Purity >99.0% (HPLC)
Manufacturer Supply Tolvaptan le Intermediates Amanang:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Lebitso | Tolvaptan |
| Lebitso la Lik'hemik'hale | N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Nomoro ea CAS | 150683-30-0 |
| Nomoro ea KAtse | RF-API101 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | Setšoantšo sa C26H25ClN2O3 |
| Boima ba Molek'hule | 448.94 |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
| Mekhoa ea ho Itsebahatsa | IR, HPLC |
| Solubility | E qhibiliha ka Benzyl Alcohol le Methanol empa ha e khone ho qhibiliha ka Metsing le Hexane |
| Mokhoa oa Bohloeki / Analysis | >99.0% (HPLC) |
| Melting Point | 219.0~222.0℃ |
| Tahlehelo ka ho Omisa | <0.50% |
| Masalla a ho Ignition | <0.10% |
| Tšilafalo e le Mong | <0.50% |
| Litšila ka Kakaretso | <1.00% |
| Litšepe tse boima | ≤20ppm |
| Metsoako e setseng | Kopana le Litlhophiso |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | API;Mekhatlo ea Meriana |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Tolvaptan (CAS: 150683-30-0), eo hape e tsejoang e le OPC-41061, ke mohanyetsi ea khethang, ea nang le tlhōlisano ea arginine vasopressin receptor 2 e sebelisetsoang ho phekola hyponatremia (maemo a tlaase a sodium ea mali) a amanang le congestive heart failure, cirrhosis, le syndrome ea hormone ea antidiuretic e sa lokelang (SIADH).Otsuka Pharmaceutical e nang le laesense ea tolvaptan tlas'a lebitso la khoebo la Samsca ka mor'a hore FDA e amohele moriana ona ka May 2009. Tolvaptan e boetse e bontšitse katleho khahlanong le lefu la liphio tsa polycystic.Tekong ea 2004, tolvaptan e tsamaisoang ka li-diuretics tsa setso e ile ea hlokomeloa hore e eketsa ho ntšoa ha metsi a feteletseng le ho ntlafatsa boemo ba sodium maling ho bakuli ba nang le lefu la pelo ntle le ho hlahisa litlamorao tse kang hypotension (khatello e tlase ea mali) kapa hypokalemia (ho fokotseha ha maemo a potasiamo maling).Setlhare se boetse se bonts'a phello e mpe mosebetsing oa liphio.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
