Tranexamic Acid CAS 1197-18-8 Assay 99.0~101.0% (Titration)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Tranexamic Acid (CAS: 1197-18-8) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka Tranexamic Acid,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Tranexamic Acid |
| Litlhaloso tse tšoanang | trans-4-(Aminomethyl) cyclohexanecarboxylic Acid;Trans-Tranexamic Acid;TAMCHA;AMCHA;HAKU;AMCA;t-AMCHA;Trans-Amcha |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 1197-18-8 |
| Foromo ea limolek'hule | C8H15NO2 |
| Boima ba Molek'hule | 157.21 g/mol |
| Melting Point | >300℃(lit.) |
| Botsitso | Hygroscopic |
| Ho qhibiliha ha Metsi | E qhibilihang ka Metsing, e batla e pepenene |
| COA & MSDS | E fumaneha |
| Mohlala oa mahala | E fumaneha |
| Tšimoloho | Shanghai, China |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Phofo e Tšoeu ea Crystalline | E lumellana |
| Solubility | E qhibiliha ka Metsing le ka Glacial Acetic Acid, E batla e sa Suluble ka Ethanol le Acetone (96%). | E lumellana |
| IR Spectrum | Tumellanong le Tranexamic Acid CRS | E lumellana |
| pH | 7.0~8.0 | 7.32 |
| Tahlehelo ka ho Omisa | <0.50% | 0.06% |
| Molora oa Sulfate | <0.10% | 0.02% |
| Litšepe tse boima (Pb) | ≤10ppm | <10ppm |
| Chloride (Cl) | ≤140ppm | <140ppm |
| Arsenic (As) | ≤2ppm | <2ppm |
| Tlhahlobo | 99.0~101.0% (ka Titration) | 99.84% |
| Lintho Tse Amanang | ||
| Tšilafalo A | <0.10% | 0% |
| Tšilafalo B | <0.20% | 0.0815% |
| Tšilafalo C | <0.10% | 0.0089% |
| Tšilafalo D | <0.10% | 0.0063% |
| Litšila ka Kakaretso | <0.20% (Ntle le A,B) | 0.015% |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se kwetswe ka thata mme o se boloke sebakeng se phodileng, se omeletseng (2~8℃) le se nang le moya o hlwekileng hole le dintho tse sa dumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Tranexamic Acid
C8H15NO2 157.2
trans-4-(Aminomethyl) cyclohexanecarboxylic acid;
Cyclohexanecarboxylic acid, 4- (aminomethyl) -, trans [1197-18-8].
TLHALOSO
Tranexamic Acid e na le NLT 99.0% le NMT 101.0% ea C8H15NO2, e baloang ho latela omisitsoeng.
TS'ELISO TS'OANE
• Infrared Absorption <197K>
TLHOKOMELO
• Tsamaiso
Mohlala oa tharollo: 140 mg ea Tranexamic Acid ka 20 ml ea glacial acetic acid
Sistimi ea Titrimetric
(Sheba Titrimetry <541>.)
Mokhoa: Titration e tobileng
Titrant: 0.1 N perchloric acid VS
Ho lemoha lintlha tsa ho qetela: Potentiometric
Tlhahlobo
Mohlala: Tharollo ea mohlala
Titrate e nang le 0.1 N perchloric acid VS, e khethollang qetello ea potentiometrically.Etsa titration e se nang letho.
ML ka 'ngoe ea 0.1 N perchloric acid e lekana le 15.72 mg ea C8H15NO2.
Mekhoa ea ho amohela: 99.0% -101.0% motheong o omisitsoeng
LITŠILA
Tšilafalo ea Inorganic
• Masalla a ho Ignition <281>: NMT 0.1%;1-g sampole e sebelisoa
• Heavy Metals, Mokhoa oa II <231>: NMT 10 ppm
• Chloride le Sulfate, Chloride <221>: Karolo ea 0.51-g ha e bontše chloride ho feta 0.1 mL ea 0.020 N hydrochloric acid (0.014%).
Litšila tsa Organic
• Tsamaiso
Mokhahlelo oa selefouno: Qhala 11.0 g ea anhydrous monobasic sodium phosphate ka 500 ml ea metsi, 'me u kenye 5 ml ea triethylamine, e lateloe ke 1.4 g ea sodium lauryl sulfate.Fetola ka acid e hlapolotsoeng ea phosphoric (10% w/w) ho pH ea 2.5, 'me u hlapolle ka metsi ho isa ho 600 mL.Kopanya tharollo ena le 400 ml ea methanol.
Tharollo ea ho tšoaneleha tsamaiso: 0.2 mg/mL ea USP Tranexamic Acid RS le 0.002 mg/mL ea USP Tranexamic Acid Related Compound C RS metsing
Tharollo e tloaelehileng: 50 µg/mL ea USP Tranexamic Acid RS ka metsing
Mohlala oa tharollo: 10 mg/mL ea Tranexamic Acid ka metsing
Sistimi ea chromatographic
(Sheba Chromatography <621>, Ho Hlokahala Sistimi.)
Mokhoa: LC
Sesebelisoa: UV 220 nm
Kholomo: 4.6-mm × 25-cm;5-µm e paka L1
Sekhahla sa phallo: 1 mL / min
Boholo ba ente: 20 µL
Nako ea ho matha: makhetlo a 3 ho feta nako ea ho boloka tranexamic acid
Ho nepahala ha sistimi
Mohlala: Tharollo ea ho lekana ha sistimi
Litlhoko tsa ho tšoaneleha
Qeto: NLT 2.0 pakeng tsa Tranexamic Acid le 0.002 mg / mL ea tranexamic acid e amanang le motsoako oa C
Tlhahlobo
Mehlala: Tharollo e tloaelehileng le Tharollo ea Mohlala
Bala liperesente tsa ho se hloeke ha motho ka mong karolong ea Tranexamic Acid e nkiloeng:
Sephetho = (rU/rS) × (CS/CU) × (0.1F)
rU = karabelo ea tlhoro bakeng sa ho se hloeke ka 'ngoe ho tsoa ho Sample solution
rS = karabelo ea tlhōrō bakeng sa tranexamic acid ho tsoa ho Standard solution
CS = khatello ea USP Tranexamic Acid RS ka har'a tharollo e tloaelehileng (µg/mL)
CU = khatello ea Tranexamic Acid ka har'a Sample solution (mg/mL)
F = ntho e amanang le karabo (sheba Letlapa la 1 la Tšilafalo)
Mekhoa ea ho amohela
Litšila tsa motho ka mong: Sheba Lethathamo la 1 la Tšilafalo.
Kakaretso ea litšila: NMT 0.2%
[Hlokomela-Hlokomela tlhoro efe kapa efe e ka tlase ho 0.025%.]
Lethathamo la 1 la Tšilafalo
Bolela Maemo a Mang a Tšebeliso ea Nako ea Karabelo e Amanang ea Karabelo Lintlha tsa Kamohelo, NMT (%).
Tranexamic acid e amanang le motsoako Aa 2.1 1 0.1
Tranexamic acid e amanang le motsoako Bb 1.5 1.2 0.2
Tranexamic acid e amanang le motsoako oa Cc 1.1 0.005 0.1
Tranexamic Acid 1.0 1.0 -
Tranexamic acid e amanang le motsoako Dd 1.3 0.006 0.1
trans,trans-4,4¢-(Iminodimethylene)di(cyclohexanecarboxylic)asiti.
b cis-4-(Aminomethyl) cyclohexanecarboxylic acid.
c (RS) -4- (Aminomethyl) cyclohex-1-enecarbocylic acid.
d 4-Aminomethyl benzoic acid.
LITEKO TSEKO
• Tahlehelo ha o Omisa <731>: Omisa 1.00 g ka 105 tlas'a vacuum bakeng sa 2 h.E lahleheloa ke NMT 0.5% ea boima ba eona.
KEKELETSO LIHLOKO
• Sephutheloana le Polokeho: Boloka ka lijaneng tse thata, 'me u li boloke mochesong o sa feteng 30.
• USP Reference Standards <11>
USP Tranexamic Acid RS Tobetsa ho Sheba Sebopeho
USP Tranexamic Acid Related Compound C RS
(RS) -4- (Aminomethyl) cyclohex-1-enecarbocylic acid.
C8H13NO2 155
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Matshwao a Kotsi Xi - E tenang
Likhoutu tsa Kotsi 36/37/38 - Ho hlohlona mahlong, tsamaiso ea ho hema le letlalo.
Tlhaloso ea Tšireletseho
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S37/39 - Apara liatlana tse loketseng le tšireletso ea mahlo / sefahleho
WGK Jeremane 2
RTECS GU8400000
HS Code 2922491100
Kotsi Class TSOHLE
Chefo LD50 ho litoeba, likhoto (mg/kg): 1500, 1200 iv (Melander)
Tranexamic Acid (CAS: 1197-18-8) is a synthetic derivative of the amino acid lysine.Tranexamic acid (e atisang ho rekisoa ka foromo ea letlapa e le Lysteda le ka mokhoa oa IV e le Cyklokapron naheng ea US le e le Transamin,Transcam Asia, le Espercil Amerika Boroa) hangata e laeloa bakeng sa ho tsoa mali ho feteletseng.Tranexamic acid ke antifibrinolytic eo ka tlholisano e thibelang ts'ebetso ea plasminogen ho plasmin, molek'hule e ikarabellang bakeng sa ho senyeha ha fibrin.Fibrin ke moralo oa motheo oa ho thehoa ha lesela la mali ka har'a hemostasis.Tranexamic acid e na le hoo e ka bang makhetlo a 8 ho feta antifibrinolytic ea analogue ea khale, ε-aminocaproic acid.E ile ea qala ho fuoa tumello ea molao ka 1957 'me ea fumana tumello ea eona ea pele ea US ka 1986. Tranexamic Acid Applicaiton E Sebelisoa e le litlolo tse soeufatsang E sebelisoa haholo litabeng tsa bongaka litabeng tsa ho buuoa, meriana ea ka hare, urology, obstetrics le gynecology, joalo-joalo ho phekola mafu a sa tšoaneng a tsoang mali le ho tsoa mali le mafu a basali. ho tsoa mali ka mokhoa o sa tloaelehang nakong ea ho buuoa, joalo-joalo E nkoa e le meriana ea hemostatic, e sebelisoang haholo-holo bakeng sa hemostasis ka mor'a ho buuoa ka matla le ka mor'a ho pepa.Ha e le hantle, hemostasis e ka 'na ea e-ba lebaka le fokolang la hore na ke hobane'ng ha litlolo tse ngata tsa meno li kenngoa ho tšepo ea ho ba le phello.
Tranexamic Acid (CAS: 1197-18-8)
Opereishene ea pelo
E sebelisoa hangata ho opereishene ea pelo, ka bobeli le ntle le ho palama pelo.E nkela aprotinin sebaka.
Ho tsoa mali ho ea khoeling
E sebelisoa e le kalafo ea pele ea nonhormonal ea ho tsoa mali ho sa sebetseng ha uterine, le mali a mangata a amanang le uterine fibroids.Phuputso ea morao-rao e bontšitse hore bakuli ba phekoloang ka tranexamic acid ba na le menyetla e mengata ea ho ba le thrombosis le necrosis ho fibroids ea bona, 'me ba ka baka bohloko le feberu.
Tšusumetso e tšoeu
Lithuto tsa bongaka ka lilemo li pakile hore tranexamic acid e ka hlapolla letheba ka nepo le ka potlako, e thusang ho bonts'a letlalo le lesoeu le khanyang le phethahetseng.Phello ea ho tlosa letheba la tranexamic acid e ka ba makhetlo a 50 ho feta Vitamin C, le makhetlo a 10 ho feta AHA.Moeli oa mahloriso oa ts'ebeliso ke 2% -3%, 'me ho litlolo chelete e ka ba 0.5%.
1. Botsitso bo botle
Ha ho bapisoa le metsoako ea setso e tšoeu, tranexamic acid e na le botsitso bo phahameng, acid le alkali resistance, 'me ha e amehe habonolo ke tikoloho ea mocheso;Ha ho ts'ireletso ea mokhanni, ha ho tšenyo ea sistimi ea phetisetso, ha ho na ts'usumetso.
2. Tsamaiso ea letlalo e bonolo ho e amohela
E loketse ka ho khetheha bakeng sa matheba a khanyang, ho soeufala le ho leka-lekanya letlalo ka kakaretso.Ntle le ho khantša matheba, tranexamic acid e ka boela ea ntlafatsa ho pepeseha ha 'mala oa letlalo ka kakaretso le ho fokola ha letlalo la lehae.
3. E ka fela matheba a matšo, matheba a mosehla, makhopho, joalo-joalo
Matheba a matšo a bakoa ke tšenyo ea UV le botsofali ba letlalo le lintlha tse ling.Ho koala acid ho ka thibela mosebetsi oa tyrosinase le melanocyte, ho fokotsa tlhahiso ea melanin ho tloha karolong ea basal ea epidermis, hape ho na le phello ea ho tlosa matheba a khubelu.
4. Tšireletseho e phahameng
Boemo bo phahameng ka ho fetisisa ba litlolo ke 2% ~ 3%.
5. Tšusumetso e tšoeu
Tranexamic Acid e loketse mefuta eohle ea letlalo bakeng sa ho tlosa pigmentation, ho soeufatsa letlalo le ho fokotsa matheba a kang: Pigmentation ka mor'a ho pepesehela letsatsi;Matheba a lefifi;Letlalo le nang le kutlo;Makhopho le ho ruruha;Tlhokomelo ea postoperative ka mor'a laser, kalafo e bobebe ea pulsed.
