Valsartan CAS 137862-53-4 Assay 98.0~102.0% API

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Valsartan

CAS: 137862-53-4

Ponahalo: Phofo e tšoeu ho isa ho e tšoeu

Tekanyo: 98.0 ~ 102.0%

API Boleng bo Phahameng, Tlhahiso ea Khoebo.Antihypertensive

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-1502674640

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Baetsi ba Lihlahisoa tsa Valsartan le Li-intermediate tse Amanang:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Valsartan
Litlhaloso tse tšoanang	N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
Nomoro ea CAS	137862-53-4
Nomoro ea KAtse	RF-API32
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C24H29N5O3
Boima ba Molek'hule	435.52
Melting Point	116.0 ~ 117.0℃
Botsitso	Hygroscopic
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e tšoeu kapa e se nang bosoeu;Ha e na monko, Hygroscopic
Boitsebiso	IR spectrum ea sampole e lumellana le spectrum e tloaelehileng ea litšupiso
Boitsebiso	Nako ea ho boloka tlhoro e kholo ea chromatogram ea boitokisetso ba tlhahlobo e lumellana le ea boitokiso bo tloaelehileng, joalo ka ha bo fumanoe ho Assay.
Solubility	E qhibiliha ka Methanol le Ethanol, Ha Ha Hanyenyane Ha E qhibiliha ka Ethylacetate, Ha Hanyenyane Hanyenyane ka Dichloromethane, Ha e qhibilihe ka Metsing
Mongobo (KF)	≤1.00%
Absorbance (420mm)	≤0.02% (λ=420nm, C=0.05g/ml, L=1cm)
Masalla a ho Ignition	≤0.10%
Litšepe tse boima	≤10ppm
D-Valsartan	≤1.00% (HPLC)
Lintho tse Amanang (HPLC)
Butyryl-Valsartan	≤0.20%
Benzyl-Valsartan	≤0.10%
Bohloeki bo sa Tsejoeng bo le Mong	≤0.10%
Litšila ka Kakaretso	≤0.30% (Ho sa kenyeletsoe D-Valsartan)
Residual Solvents (GC)
Methanol	≤3000ppm
Ethyl Acetate	≤5000ppm
N, N-Dimethylformamide	≤880ppm
Toluene	≤890ppm
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC e baloa ho latela anhydrous, solvent-free basis)
Tekanyetso ea Teko	United States Pharmacopoeia (USP)
Tšebeliso	Active Pharmaceutical ingredient (API)

Valsartan (CAS: 137862-53-4) Phallo ea Ts'ebetso ea Tlhahiso

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Valsartan (CAS: 137862-53-4) e nang le boleng bo phahameng.Valsartan ke mohanyetsi oa nonpeptide angiotensin II AT1 receptor, Antihypertensive, e na le monyetla oa ho etsa lipatlisiso tsa khatello e phahameng ea mali le ho hloleha ha pelo.
Litlamorao tsa Valsartan tsa antihypertensive li matla ho feta tsa enalapril mme e loketse ho alafa khatello ea mali, khatello ea mali e tlase ho isa ho e leka-lekaneng, haholoholo khatello ea mali ea bobeli e bakoang ke tšenyo ea renal.E ka fokotsa haholo proteinuria bakeng sa bakuli ba khatello ea mali ba nang le lefu la tsoekere kapa mesebetsi e tloaelehileng ea sebete, 'me e ka khothaletsa uric acid le sodium ea moroto ho sireletsa liphio.Valsartan e boetse e loketse ho fokotsa lefu la pelo ho bakuli ba kotsing e kholo (ho se sebetse hantle ha ventricular kapa ho se sebetse hantle) kamora ho tšoaroa ke lefu la pelo.