Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality
Phepelo ea Vonoprazan Fumarate le ea Mahareng e Amanang
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Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Lebitso la Lik'hemik'hale | Vonoprazan Fumarate |
| Litlhaloso tse tšoanang | TAK-438 |
| Nomoro ea CAS | 1260141-27-2;881681-01-2 |
| Nomoro ea KAtse | RF-API99 |
| Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
| Foromo ea limolek'hule | Setšoantšo sa C21H20FN3O6S |
| Boima ba Molek'hule | 461.463 |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e tšoeu kapa e batlile e tšoeu |
| Boitsebiso ba 1 H-NMR | E lumellana le Maemo |
| Boitsebiso ba IR | The IR Absorption spectrum ea sampole concordant le litšupiso standard |
| Boitsebiso ba HPLC | Nako ea ho boloka sampole e lumellana le maemo a referense |
| Litaba tsa Metsi | ≤0.50% |
| Masalla a ho Ignition | ≤0.20% |
| Heavy Metals (as Pb) | ≤20ppm |
| Lintho Tse Amanang | |
| Tšilafalo A | ≤0.20% |
| Tšilafalo B | ≤0.15% |
| Tšilafalo C | ≤0.15% |
| Tšilafalo E 'ngoe | ≤0.10% |
| Litšila ka Kakaretso | ≤1.0% |
| Metsoako e setseng | |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| Ethyl Acetate | ≤0.50% |
| Mokhoa oa ho hlahloba / oa ho hlahloba | 98.0%~102.0% (Ka HPLC) |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | API |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli, mongobo.
Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), proton pump inhibitor (PPI), ke motsoako o matla le o sebetsang ka molomo oa potassium-competitive acid blocker (P-CAB), e nang le antisecretory. mosebetsi.Vonoprazan Fumarate e thibela ts'ebetso ea H+,K+-ATPase ho li-microsome tsa porcine gastric tse nang le IC50 ea 19 nM ho pH 6.5.Vonoprazan Fumarate (Takecab), e fumanoeng le ho ntlafatsoa ke Takeda le Otsuka, e ile ea amoheloa ke PMDA ea Japane ka December 2014. Vonoprazan Fumarate e sebelisoa haholo-holo bakeng sa phekolo ea tšoaetso ea helicobacter pylori, reflux ea gastroesophageal, peptic ulcer, duodenal ulcer, esophagitis, gas. seso le mafu a mang a amanang le asiti ea ka mpeng.Sehlahisoa se na le thibelo e matla, e tšoarellang ea secretion ea gastric acid.Ka tekanyetso ea kalafo, Vonoprazan Fumarate ha e na phello e nyane ho li-enzyme tse ling hape e na le phello e nyane mesebetsing ea 'mele ea' mele.E bolokehile ebile e mamelleha haholoanyane.
