2-(Chloromethyl) -4-Methylquinazoline CAS 109113-72-6 Linagliptin Intermediate Purity ≥99.0% (HPLC)
Produsén Pasokan Linagliptin sareng Panganteur Patali:
Linagliptin CAS 668270-12-0
Linagliptin Induk inti CAS panengah 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
2-(Klorométil)-4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino)piperidin CAS 309956-78-3
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0
Ngaran Kimia | 2- (Klorométil) -4-Methylquinazoline |
sinonim | Linagliptin Intermediate A |
Nomer CAS | 109113-72-6 |
Nomer CAT | RF-PI498 |
Status saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C10H9ClN2 |
Beurat Molekul | 192.64 |
Kapadetan | 1.251 |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bulak Konéng nepi Bulak Brown Bubuk |
Idéntifikasi A | Sampel spéktrum IR kedah cocog sareng spéktrum standar |
Idéntifikasi B | Waktu ingetan tina puncak prinsip sampel kudu luyu jeung standar |
Kalarutan | Leyur dina métilén klorida;Teu leyur dina Cai |
Kamurnian / Métode Analisis | ≥99,0% (HPLC) |
Titik Lebur | 60,0 nepi ka 65,0 ℃ |
Cai (KF) | ≤0,50% |
Résidu on Ignition | ≤0,50% |
Zat Patali | |
Najis Tunggal | ≤0,30% |
Total Kotoran | ≤1,0% |
Standar tés | Standar Perusahaan |
Pamakéan | Panengah pikeun Linagliptin (CAS: 668270-12-0) |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.
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2-(Chloromethyl)-4-Methylquinazoline (CAS: 109113-72-6) dianggo salaku perantara pikeun persiapan Linagliptin (CAS: 668270-12-0), sareng najisna.Linagliptin, dijual kalayan nami merek Tradjenta diantarana, mangrupikeun ubar anu dianggo pikeun ngubaran diabetes mellitus tipe 2. Umumna kirang langkung dipikaresep tibatan metformin sareng sulfonylureas salaku pengobatan awal.Hal ieu dipaké babarengan jeung latihan jeung diet.Henteu disarankeun pikeun diabetes tipe 1.Gawéna ku ningkatkeun produksi insulin sareng ngirangan produksi glukagon ku pankréas.Linagliptin disatujuan pikeun panggunaan médis di Amérika Serikat dina taun 2011. Linagliptin mangrupikeun sambetan dipeptidyl peptidase-4 (DPP-4) selektif anu pohara kuat sareng IC50 tina 1 nM.
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