2-Methyltryptamine CAS 2731-06-8 Purity > 99,0% (HPLC) Panobinostat Intermediate Factory Kualitas Luhur
Produsén Pasokan Sareng Kualitas Tinggi, Produksi Komersil
Ngaran kimiawi: 2-Methyltryptamine CAS: 2731-06-8
Ngaran Kimia | 2-Metiltriptamin |
sinonim | 2-Methylindole-3-Étilamin;2-(2-Metil-1H-indol-3-yl)étanamin;3-(2-Aminoetil)-2-Methylindole |
Nomer CAS | 2731-06-8 |
Nomer CAT | RF-PI1480 |
Status Saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C11H14N2 |
Beurat Molekul | 174.25 |
Titik Lebur | 106,0 nepi ka 110,0 ℃ |
Titik didih | 177 ℃ / 1,5 mmHg (lit.) |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Coklat Padet |
Purity / Métode Analisis | > 99,0% (Area HPLC) |
1-HNMR | Konsisten Jeung Struktur |
Leungitna dina Drying | <1,00% |
Najis Tunggal | <0,50% |
Total Kotoran | <1,00% |
Logam beurat (sakumaha Pb) | <20ppm |
Standar tés | Standar Perusahaan |
Pamakéan | Panganteur Farmasi;Panobinostat panengah |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.
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2-Methyltryptamine (CAS: 2731-06-8) mangrupikeun bahan awal konci dina sintésis Panobinostat (LBH589) (CAS: 404950-80-7).Panobinostat mangrupakeun inhibitor potent sadaya deacetylases histone (HDACs), kalawan nilai Ki mimitian ti 0,6 nepi ka 31 nM pikeun HDAC1-11.Ngaliwatan aksi ieu, éta ngabalukarkeun acetylation sauntuyan protéin sélular, hasilna ditewak siklus sél jeung apoptosis dina sél kanker.Panobinostat mangrupikeun inhibitor HDAC munggaran anu disatujuan ku FDA pikeun pengobatan sababaraha myeloma.Panobinostat dipasarkan salaku Farydak, dipaké dina kombinasi kalayan Bortezomib (CAS: 179324-69-7) jeung Dexamethasone (CAS: 50-02-2) pikeun ngubaran sababaraha myeloma relapsed sanggeus perlakuan saméméh Bortezomib na immunomodulator.
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