2,4,5-Asam Trifluorophenylacetic CAS 209995-38-0 Purity ≥99,5% (GC) Sitagliptin Fosfat Monohydrate Panengah
Pasokan Sitagliptin Phosphate Monohydrate Related Intermediate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Asam Trifluorophenylacetic CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Asam Butyric CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Ngaran Kimia | 2,4,5-Asam Trifluorophenylacetic |
Nomer CAS | 209995-38-0 |
Nomer CAT | RF-PI1191 |
Status Saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C8H5F3O2 |
Beurat Molekul | 190.12 |
Titik Lebur | 121,0 nepi ka 125,0 ℃ |
Kalarutan | Leyur dina Métanol |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bodas ka Pareum-Bodas Bubuk |
Purity / Métode Analisis | ≥99,5% (GC) |
Kelembapan (KF) | ≤0,50% |
Résidu on Ignition | ≤0,50% |
Total Kotoran | ≤0,50% |
Standar tés | Standar Perusahaan |
Pamakéan | Panganteur Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.
Asam 2,4,5-Trifluorophenylacetic (CAS: 209995-38-0) mangrupikeun perantara tina Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) dianggo pikeun ngubaran DM tipe 2 sabab ningkatkeun kontrol glikemik ku cara ningkatkeun tingkat hormon incretin aktif, GLP-1 (péptida-1) sareng GIP (péptida insulinotropik anu gumantung kana glukosa).Aktivasina incretins ieu dina sél β-pankréas ngabalukarkeun ngaronjat tingkat siklik adénosin monofosfat (cAMP) jeung kalsium intrasélular, kalawan sékrési insulin gumantung glukosa saterusna (2).Ubar hipoglikemik ieu kagolong kana kelas anyar anu disebut inhibitor dipeptidyl peptidase IV.STG disatujuan ku FDA dina 2006.