3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 Olaparib Panengah Pabrik
Purity High, Produksi komérsial
Olaparib sareng Panganteur Patali:
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3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
Ngaran Kimia | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
sinonim | Dimétil 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate |
Nomer CAS | 61260-15-9 |
Nomer CAT | RF-PI453 |
Status saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C10H11O5P |
Beurat Molekul | 242.17 |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bubuk Bodas atanapi Méh Bodas |
Kasucian | ≥98,0% |
Kelembapan (KF) | ≤0,50% |
Total Kotoran | ≤2,0% |
Standar tés | Standar Perusahaan |
Pamakéan | Panengah Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), panengah Olaparib (CAS: 763113-22-0).Olaparib mangrupakeun jenis novél ADP-ribosa polimérase (PARP) inhibitor, kaasup PARP1, PARP2, sarta PARP3.PARP mediates mékanisme DNA-repair nu muterkeun hiji peran penting dina perbaikan karuksakan DNA jeung apoptosis, jadi olaparib husus nargétkeun dina mékanisme perbaikan DNA tina targeting perbaikan DNA sél jeung mawa pangaruh ku narajang kerentanan kritis sél kanker mawa mutasi dina BRCA1 jeung BRCA2.Kusabab mékanisme ieu, éta tiasa dianggo pikeun terapi pangropéa pasien kanker ovarium kambuh parah anu ngagaduhan mutasi gen kerentanan kanker payudara (BRCA) ogé sénsitip kana ubar platinum.