4- [(1-Pyrrolidinylsulfonyl) métil] anilin CAS 334981-10-1 Purity> 99,0% (HPLC) Pabrik Almotriptan Aniline prékursor
Pasokan Kimia Ruifu Almotriptan Malate panengah:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4- [(1-Pyrrolidinylsulfonyl)métil] anilin CAS 334981-10-1
1-[(4-Nitrofenilmétil)sulfonil]pirolidin CAS 340041-91-0
4-Chlorobutyraldehyde Dietil Acetal CAS 6139-83-9
Ngaran Kimia | 4- [(1-Pyrrolidinylsulfonyl) métil] anilin |
sinonim | 1- [(4-Aminobenzyl)sulfonil]pirolidin;Almotriptan Aniline prékursor |
Nomer CAS | 334981-10-1 |
Nomer CAT | RF-PI1948 |
Status Saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C11H16N2O2S |
Beurat Molekul | 240.32 |
Titik lebur | 170,0 nepi ka 176,0 ℃ |
Kapadetan | 1.31 |
Kalarutan | Rada leyur dina Toluene |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bubuk kristalin bodas nepi ka samar konéng |
Purity / Métode Analisis | > 99,0% (HPLC) |
Leungitna dina Drying | <0,50% |
Résidu on Ignition | <0,50% |
Max Single Impurity | <0,50% |
Total Kotoran | <1,00% |
Logam beurat | <20ppm |
Spéktrum Infrabeureum | Conforms kana Struktur |
NMR | Conforms kana Struktur |
Standar tés | Standar Perusahaan |
Pamakéan | Almotriptan Aniline prékursor |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap
4- [(1-Pyrrolidinylsulfonyl)métil] anilin (CAS: 334981-10-1) mangrupa perantara dina persiapan Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline prékursor.Almotriptan Malate mangrupikeun ubar triptan anu tiasa dianggo pikeun ngubaran nyeri sirah.Almotriptan kagolong kana kategori ubar tina agonis reséptor serotonin selektif.Almotriptan gaduh afinitas anu luhur sareng spésifisitas pikeun reséptor serotonin 5-HT, salajengna ngarah kana vascoconstriction pembuluh darah otak sareng mangaruhan redistribusi aliran getih.Épék ieu ngeureunkeun sinyal nyeri tina dikirim ka uteuk, sareng salajengna ngahambat sékrési zat alami anu nyababkeun nyeri, seueul sareng gejala migrain sanés.Tapi, Almotriptan henteu nyegah serangan migrain.Almotriptan, dipasarkan di 2000, boga oralbioavailability pangluhurna diantara sakabeh triptans.Almotriptan dimetabolisme ku MAO-A sareng CYP3A4, sahingga gaduh profil épék samping anu langkung nguntungkeun upami dibandingkeun sareng Sumatriptan.