5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Pabrik Panganteur Dapagliflozin
Produsén Supply, Purity High, Produksi komérsial
Dapagliflozin (CAS: 461432-26-8) Panganteur Patali:
5-Bromo-2-Asam Klorobenzoat CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Ngaran Kimia | 5-Bromo-2-Asam Klorobenzoat |
| sinonim | 2-Chloro-5-Asam Bromobenzoat |
| Nomer CAS | 21739-92-4 |
| Nomer CAT | RF-PI439 |
| Status saham | Dina Stok, Skala Produksi Nepi ka Ton |
| Formula Molekul | C7H4BrClO2 |
| Beurat Molekul | 235.46 |
| Titik Lebur | 154,0 nepi ka 156,0 ℃ (lit.) |
| merek | Kimia Ruifu |
| Barang | spésifikasi |
| Penampilan | Pareum-Bodas mun Lampu Konéng Bubuk |
| Assay | ≥99,0% |
| Cai (KF) | ≤0,50% |
| Résidu on Ignition | ≤0,30% |
| 2-Asam klorobenzoat | ≤0,30% |
| 2-Chloro-3-Asam Bromobenzoat | ≤0,30% |
| Total Kotoran | ≤1,0% |
| Standar tés | Standar Perusahaan |
| Pamakéan | Panengah Dapagliflozin (CAS: 461432-26-8), diabetes tipe II |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.
Asam 5-Bromo-2-Chlorobenzoic (CAS: 21739-92-4) dianggo salaku bahan awal dina sintésis Dapagliflozin (CAS: 461432-26-8), sambetan kotransporter-2 natrium-glukosa selektif anu ngirangan ginjal. reabsorpsi glukosa sareng dianggo pikeun ngubaran pasien kalayan diabetes tipe II.Dapagliflozin mangrupikeun inhibitor SGLT-2 (SLC5A2) anu kuat sareng selektif kalayan EC50 1,1 nM.Cai mibanda perméabilitas anu saé dina mémbran sél Caco-2 sareng mangrupikeun substrat pikeun P-glikoprotein (P-gp).Dapagliflozin disatujuan dina 2012 ku FDA.
