7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Purity> 99,0% (HPLC) Afatinib Dimaleate Intermediate Factory

Katerangan pondok:

Ngaran: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Kamurnian: > 99,0% (HPLC)

Penampilan: Lampu Konéng nepi Light Brown Bubuk

Panganteur Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Katerangan:

Panganteur Pasokan Kimia Ruifu of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Dietil Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Asam Dietilphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-hiji CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5

Sipat Kimia:

Ngaran Kimia	7-Chloro-6-Nitro-4-Hydroxyquinazoline
sinonim	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4 (3H) -Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-hiji;7-Chloro-6-Nitroquinazolin-4 (3H) -hiji
Nomer CAS	53449-14-2
Nomer CAT	RF-PI2030
Status saham	Dina Stok, Skala Produksi Nepi ka Ton
Formula Molekul	C8H4ClN3O3
Beurat Molekul	225.59
Sensitipitas	Sensitip Panas
Kalarutan	Rada Leyur dina Dimethylformamide
merek	Kimia Ruifu

spésifikasi:

Barang	spésifikasi
Penampilan	Lampu Konéng nepi Light Brown Bubuk
Idéntifikasi (HPLC)	Waktos Panyimpenan Sampel Kedah Cocog sareng Standar
Purity / Métode Analisis	> 99,0% (HPLC)
Titik lebur	300.0 ~ 303.0 ℃
Kandungan Cai (KF)	<0,50%
Résidu on Ignition	<0,30%
Najis 1	<0,50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
Najis 2	<0,50% (5,7-Dichloro-4[1H]quinazolinone)
Najis 3	<1,00% (7-Chloro-8-Nitro-4[1H]quinazolinone)
Séjén Najis Tunggal	<0,20%
Total Kotoran	<1,00%
Logam beurat (sakumaha Pb)	<20ppm
Spéktrum Infrabeureum	Conforms kana Struktur
Proton NMR Spéktrum	Proton NMR Spéktrum
Standar tés	Standar Perusahaan
Pamakéan	Panganteur Afatinib, Afatinib Dimaleate

Paket & Panyimpenan:

Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang

Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap

Kaunggulan:

FAQ:

Aplikasi:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) mangrupa panengah Afatinib Dimaleate (CAS: 850140-73-7).Afatinib mangrupikeun kulawarga pameungpeuk ErbB anu teu tiasa dibalikkeun anu nyegah pangiriman inpormasi sareng ngahalangan jalur utama anu aya dina kamekaran sareng pamisahan sél kanker.Kusabab mékanisme transduksi inpormasi kulawarga ErbB tiasa dipicu ku sababaraha homodimer sareng heterodimer, inhibisi sakaligus sababaraha anggota kulawarga ErbB (sapertos EGFR, HER2, ErbB3 sareng ErbB4) tiasa sacara efektif ngaganggu transduksi inpormasi hilir.Afatinib dipaké pikeun ngubaran hiji tipe tangtu kanker paru (non-sél leutik kanker paru) nu geus sumebar ka bagian séjén awak.Éta kagolong kana kelas ubar anu katelah sambetan kinase.Gawéna ku ngalambatkeun atanapi ngeureunkeun kamekaran sél kanker.Éta ngiket kana protéin tangtu (réséptor épidermal-EGFR) dina sababaraha tumor.