Atazanavir CAS 198904-31-3 Purity ≥99.0% Pabrik API Anti-HIV HIV-1 Protéase Inhibitor
Pasokan sareng Purity High sareng Kualitas Stabil
Ngaran Kimia: Atazanavir
CAS: 198904-31-3
HIV-1 Protéase Inhibitor
API Quality High, Produksi komérsial
Ngaran Kimia | Atazanavir |
sinonim | BMS-232632 |
Nomer CAS | 198904-31-3 |
Nomer CAT | RF-API70 |
Status saham | Dina Stok, Skala Produksi Nepi ka Ratusan Kilogram |
Formula Molekul | C38H52N6O7 |
Beurat Molekul | 704.86 |
Titik lebur | 207,0 ~ 209,0 ℃ |
Kalarutan | Leyur dina DMSO;Teu leyur dina Cai |
Panyimpenan Jangka Panjang | Nyimpen jangka panjang dina -20 ℃ |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bubuk Bodas |
Wangun | Dasar bébas |
Leungitna dina Drying | ≤0,50% |
Résidu on Ignition | ≤0,20% |
Logam beurat | ≤20ppm |
Najis A | ≤0,10% |
Najis B | ≤0,10% |
Najis Tunggal | ≤0,20% |
Total Kotoran | ≤1,0% |
Purity / Métode Analisis | ≥99,0% (HPLC) |
pH | 5.0~8.0 |
Standar tés | Standar Perusahaan |
Pamakéan | HIV-1 Protéase Inhibitor Anti-HIV |
Bungkusan: Botol, kantong aluminium foil, kardus Drum, 25kg / Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya, Uap jeung infestation hama.
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Atazanavir (CAS 198904-31-3) mangrupikeun antiretroviral, novél sareng ubar azapeptide anu kuat tina kelas inhibitor protease (PI).Éta dijual kalayan nami dagang Reyataz.Sapertos antiretrovirals sanés, éta dianggo pikeun ngubaran inféksi virus immunodeficiency manusa tipe 1 (HIV-1) énzim protease kalayan konstanta inhibisi Ki 66 nmol/L sareng ogé ngahambat réplikasi virus HIV-1 kalayan konsentrasi efektif 50% EC50 mimitian ti. 2,6 nepi ka 5,3 nmol/L.Atazanavir ngiket protease HIV-1 nyegah pembelahan poliprotein gag sareng gag-pol, anu nyababkeun formasi virion anu teu dewasa dina sél anu kainféksi HIV-1.Atazanavir gaduh struktur kimia simetri C-2 anu béda sareng poténsi antiretroviral umumna langkung ageung dina sababaraha galur HIV dibandingkeun sareng sambetan protease sanés, kalebet Indinavir, Nelfinavir, Ritonavir, Saquinavir sareng Amprenavir.Atazanavir dibédakeun tina PI sanés anu tiasa dipasihkeun sakali sadinten sareng gaduh pangaruh anu langkung handap dina profil lipid pasien.Sapertos sambetan protease sanés, éta ngan ukur dianggo digabungkeun sareng pangobatan HIV anu sanés.Atazanavir mangrupikeun inhibitor protease HIV azapeptide novel.Antiviral.Ieu dicokot ku sungut sakali sapoé.
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