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Ibrutinib Intermediate CAS 330792-70-6 Purity > 98,0% (HPLC) Gambar Unggul
  • Ibrutinib Intermediate CAS 330792-70-6 Purity >98,0% (HPLC)

Ibrutinib Intermediate CAS 330792-70-6 Purity >98,0% (HPLC)

Katerangan pondok:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Kamurnian: > 98,0% (HPLC)

Penampilan: Pareum-bodas nepi ka bubuk konéng lampu

Panganteur Ibrutinib (CAS: 936563-96-1) 

Kontak: Dr Alvin Huang

Mobile / Wechat / WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Panganteur Ibrutinib:

Ibrutinib CAS 936563-96-1
3-Hydroxypiperidine CAS 6859-99-0
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S) -1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Asam Phenoxybenzoic CAS 2215-77-2
4-Asam Phenoxyphenylboronic CAS 51067-38-0
4-Aminopyrazolo [3,4-d] pirimidin CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pirimidin CAS 151266-23-8
Ibrutinib Deacrylylpiperidine CAS 330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Sipat Kimia:

Ngaran Kimia 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
sinonim Ibrutinib panengah N-3;3-Amino-5-(4-Phenoxyphenyl)pirazol-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pirazol;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Nomer CAS 330792-70-6
Status Saham Dina Stok, Skala Produksi Nepi ka Ton
Formula Molekul C16H12N4O
Beurat Molekul 276.29
Kapadetan 1,37±0,10 g/cm3
COA & MSDS Aya
Asalna Shanghai, Cina
merek Kimia Ruifu

spésifikasi:

Barang spésifikasi
Penampilan Pareum-Bodas mun Lampu Konéng Bubuk
Purity / Métode Analisis > 98,0% (HPLC)
Leungitna dina Drying <1,00%
Résidu on Ignition <0,50%
Total Kotoran <2.00%
Logam beurat (sakumaha Pb) <20ppm
1 H NMR Spéktrum Konsisten jeung Struktur
Standar tés Standar Perusahaan
Pamakéan Panganteur Ibrutinib (CAS: 936563-96-1)

Paket & Panyimpenan:

Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.

Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.

Kaunggulan:

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330792-70-6 - Aplikasi:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) mangrupa perantara Ibrutinib (CAS: 936563-96-1).Ibrutinib nunjukkeun pangaruh ngahambat anu kuat sareng teu tiasa malik sareng selektivitas pikeun kagiatan énzimatik Btk.Dina jalur sél DOHH2 anu diaktipkeun jalur BCR, Ibrutinib ngahambat autofosforilasi Btk, fosforilasi substrat fisiologis Btk PLCγ, sareng fosforilasi kinase hilir salajengna, ERK sareng IC50 tina 11 nM, 29 nM sareng 13 nM, masing-masing.Ibrutinib nunjukkeun induksi sitotoksisitas anu gumantung kana dosis sareng gumantung kana waktos dina sél leukemia limfositik kronis (CLL).Sajaba ti éta, Ibrutinib induces maot sél gumantung kana aktivasina jalur caspase sarta antagonizes kamampuh sél CLL proliferasi sanggeus TLR signalling.

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