LCZ696 Panengah CAS 1426129-50-1 Purity ≥98.0% (HPLC) ee ≥99.0% Pabrik High Purity
Pasokan komérsial LCZ696 (CAS: 936623-90-4) Patali Patali:
(R)-tert-Butyl (1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate CAS: 1426129-50-1
(R,E)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid CAS: 1012341-50-2
(2R,4S)-étil 5-(1,1'-biphenyl-4-yl)-4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (hemicalcium uyah) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
LCZ696;Entresto;Campuran Sacubitril sareng Valsartan CAS: 936623-90-4
| Ngaran Kimia | (R)-tert-Butyl (1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate |
| sinonim | LCZ696 panengah |
| Nomer CAS | 1426129-50-1 |
| Nomer CAT | RF-PI169 |
| Status saham | Dina Stok, Skala Produksi Nepi ka Ratusan Kilogram |
| Formula Molekul | C20H25NO3 |
| Beurat Molekul | 327.42 |
| merek | Kimia Ruifu |
| Barang | spésifikasi |
| Penampilan | Bodas ka Pareum-Bodas Bubuk |
| Kamurnian / Métode Analisis | ≥98,0% (HPLC) |
| Kaleuwihan enantiomérik | ee: ≥99,0% |
| Kelembapan (KF) | ≤1,0% |
| Bahan Patali A | ≤1,0% (RRT=0,5) A=(R)-3-([1,1'-biphenyl]-4-yl)-2-aminopropan-1-ol |
| Bahan Patali B | ≤1.0% (RRT=0.85) B=Triphenylphosphine oxide |
| Zat lianna | ≤1,0% |
| Total Kotoran | ≤2,0% |
| Standar tés | Standar Perusahaan |
| Pamakéan | Panengah LCZ696 (CAS: 936623-90-4) dina pengobatan HFrEF |
Bungkusan: Botol, kantong Aluminium foil, kardus drum, 25kg / Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya, Uap jeung infestation hama.
Produsén kalawan Purity High sarta Quality Stabil
Pasokan komérsial LCZ696 (CAS: 936623-90-4) Patali Patali:
(R)-tert-Butyl (1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate CAS: 1426129-50-1
(R,E)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid CAS: 1012341-48-8
(2R,4S)-5-(1,1'-biphenyl-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid CAS: 1012341-50-2
(2R,4S)-étil 5-(1,1'-biphenyl-4-yl)-4-amino-2-methylpentanoate HCl CAS: 149690-12-0
AHU-377 (hemicalcium uyah) CAS: 1369773-39-6
AHU-377;Sacubitril CAS: 149709-62-6
LCZ696;Entresto;Campuran Sacubitril sareng Valsartan CAS: 936623-90-4
LCZ696 mangrupikeun ubar ékspérimén anu dikembangkeun ku Novartis Pharmaceutical Amérika Serikat pikeun pengobatan pasien Gagal Jantung sareng Fraksi Ejection anu ngirangan (HFrEF).Gagal jantung mangrupikeun panyakit anu ngancam kahirupan.Jantung sabar teu bisa ngompa cukup getih pikeun nyadiakeun awak, sarta muncul gejala dyspnea, kacapean jeung ingetan cairan lalaunan, lajeng laun ngaronjat, nyata mangaruhan kualitas hirup.LCZ696 tiasa ningkatkeun pertahanan alami awak ngalawan gagal jantung, ogé ningkatkeun tingkat péptida natriuretik sareng péptida vasoaktif endogen anu sanés, sareng ngahambat sistem renin-angiotensin-aldosteron (RAAS).LCZ696 parantos digabungkeun sareng Novartis's Hypertension Medication (Diovan, nami generik: valsartan) sareng ubar eksperimen AHU-377.AHU377 ngahalangan mékanisme dua péptida anu tanggung jawab pikeun nurunkeun tekanan darah.Diovan ningkatkeun vasodilatasi sareng ngarangsang awak pikeun ngaluarkeun natrium sareng cai.
