Lenvatinib Mesylate Intermediate CAS 15568-85-1 Purity> 97,0% (HPLC) Gambar Unggul Pabrik

Lenvatinib Mesylate Intermediate CAS 15568-85-1 Purity > 97,0% (HPLC) Pabrik

Katerangan pondok:

5-(Methoxymethylene)-2,2-Dimétil-1,3-Dioxane-4,6-Dione

CAS: 15568-85-1

Kamurnian: > 97,0% (HPLC)

Penampilan: Bubuk konéng

Panganteur Lenvatinib Mesylate CAS 857890-39-2

Kontak: Dr Alvin Huang

Mobile / Wechat / WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Katerangan:

Ruifu Kimia Supply Lenvatinib Mesylate panengah Jeung Purity High
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Métil 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Métil 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimétil-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Métil 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Sipat Kimia:

Ngaran Kimia	5-(Methoxymethylene)-2,2-Dimétil-1,3-Dioxane-4,6-Dione
sinonim	5- (Methoxymethylene) Asam Meldrum;Cabozantinib Impurity 56;Najis Lenvatinib 79
Nomer CAS	15568-85-1
Nomer CAT	RF-PI1967
Status Saham	Dina Stok, Skala Produksi Nepi ka Ton
Formula Molekul	C8H10O5
Beurat Molekul	186.16
Titik lebur	132,0 ~ 134,0 ℃
Kapadetan	1,297±0,06 g/cm3
merek	Kimia Ruifu

spésifikasi:

Barang	spésifikasi
Penampilan	Bubuk konéng
1 H NMR Spéktrum	Konsisten Jeung Struktur
Purity / Métode Analisis	> 97,0% (HPLC)
Total Kotoran	<3,00%
Standar tés	Standar Perusahaan
Pamakéan	Panganteur Lenvatinib Mesylate (CAS: 857890-39-2)

Paket & Panyimpenan:

Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang

Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap

Kaunggulan:

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Aplikasi:

5- (Methoxymethylene) -2,2-Dimétil-1,3-Dioxane-4,6-Dione (CAS: 15568-85-1) mangrupa perantara Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib mangrupikeun ubar kanker tiroid anu dikembangkeun ku Eisai Corporation of Japan (Kode: E7080), milik inhibitor of oral multi-receptor tyrosine kinase (RTK) sareng tiasa ngahambat kagiatan kinase tina faktor pertumbuhan endothelial vaskular (VEGF) Reséptor VEGFR1 ( FLT1), VEGFR2 (KDR), sareng VEGFR3 (FLT4).Lenvatinib ogé bisa ngahambat involvement of RTKs séjén dina angiogenesis patologis, tumuwuhna tumor, sarta progression kanker iwal fungsi sélular normal maranéhanana kaasup fibroblast growth factor (FGF) reséptor FGFR1, 2, 3, jeung 4;reséptor faktor pertumbuhan turunan trombosit (PDGFR [alfa]), KIT, sareng RET.[Indikasi]: Lenvatinib cocog pikeun pengobatan pasien kanker tiroid kambuh lokal atanapi tipe metastasis, tipe progressivity jeung tipe differentiated iodin-refractory radioaktif.Dina Pébruari 13, 2015, FDA AS disatujuan ubar antikanker Lenvatinib pikeun pengobatan kanker tiroid.Lenvatinib mangrupikeun inhibitor énzim multi-target, sanggup ngahambat VEGFR2 sareng VEGFR3 (reséptor faktor pertumbuhan endothelial vaskular).Ngaran dagang Lenvatinib nyaéta Lenvima.Dina 20 Méi 2015, Badan Obat Éropa (EMA) disatujuan Lenvatinib pikeun pengobatan kanker tiroid invasif, maju sacara lokal atanapi metastatik (papillary, follicular, Hurthle type) kanker tiroid (DTC).Dina sidang, waktu survival median pikeun penderita radioaktif iodin-refractory DTC diperlakukeun kalayan Lenvatinib éta 18 bulan bari nilai pikeun penderita anu nyandak placebo ngan 3 bulan.