Levosimendan Intermediate CAS 36725-28-7 Purity > 99,5% (HPLC) Pabrik
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone (CAS: 36725-28-7) with high quality, commercial production. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com
Ngaran Kimia | 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone |
sinonim | 6- (p-Aminophenyl) -5-métil-4,5-dihydro-3 (2H) -pyridazinone;1,4-Dihydro-4-Methyl-3-(4-Aminophenyl)pyridazine-6(5H)-hiji ;Najis Levosimendan 5 |
Nomer CAS | 36725-28-7 |
Nomer CAT | RF-PI1976 |
Status Saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C11H13N3O |
Beurat Molekul | 203.25 |
Titik lebur | 194,0 nepi ka 198,0 ℃ |
Kapadetan | 1,30 ± 0,10 g / cm3 |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Pareum-Bodas nepi ka Bulak Bubuk Warna Coklat |
Idéntifikasi (HPLC) | HPLC RT tina puncak utama pakait sareng standar kerja di-imah |
Leungitna dina Drying | <0,50% |
Résidu on Ignition | <0,20% |
Zat Patali | (HPLC) |
Najis Tunggal | <0,20% |
Total Kotoran | <0,50% |
Purity / Métode Analisis | > 99,5% (HPLC) |
Logam beurat | <20ppm |
Proton NMR Spéktrum | Conforms kana Struktur |
Standar tés | Standar Perusahaan |
Pamakéan | Panengah Levosimendan (CAS: 141505-33-1) |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap
6- (4-Aminophenyl) -4,5-Dihydro-5-Methyl-3 (2H) -Pyridazinone (CAS: 36725-28-7) mangrupa panengah Levosimendan (CAS: 141505-33-1).Levosimendan diwanohkeun di Swedia salaku infus iv pikeun pengobatan gagal jantung akut atanapi gejala refractory gagal jantung kronis dina kasus dimana perlakuan konvensional (contona, diuretik atanapi inhibitor ACE) henteu cekap.Éta ogé ngaktifkeun ventricular sareng arteri adenostne trifosfat-diatur saluran kalium anu nyababkeun vasodilatasi dina otot lemes vaskular sareng ngajagaan miokardium tina infark.Aktivitas ngahambat fosfodiesterase III anu rendah sigana henteu tanggung jawab kana épék inotropik, lusitropik sareng dilating anu positif.Beda sareng ubar kardiotonik sanés, levosimendan tiasa ngahasilkeun épék inotropik anu positif tanpa manjangkeun rélaxasi miokard atanapi ningkatkeun insiden aritmia ganas.Éta sacara klinis nunjukkeun résiko mortalitas anu langkung handap dina pasien anu gagal jantung dibandingkeun sareng plasebo sareng dobutamine.Kusabab éta ngagaduhan poténsi anu langkung ageung, levosimendan ayeuna nuju dina evaluasi klinis salajengna salaku pangobatan kronis pikeun gagal jantung kongestif.