Métil 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 Purity > 98,0% (HPLC) Lenvatinib Mesylate Intermediate Factory
Ruifu Kimia Supply Lenvatinib Mesylate panengah Jeung Purity High
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Métil 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Métil 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimétil-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Métil 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Ngaran Kimia | Métil 4-Chloro-7-Methoxyquinoline-6-Carboxylate |
sinonim | Lenvatinib Impurity 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Métil Éster;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Asam Métil Éster;Lenvaint-D |
Nomer CAS | 205448-66-4 |
Nomer CAT | RF-PI1970 |
Status Saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C12H10ClNO3 |
Beurat Molekul | 251.67 |
Titik didih | 377,4 ± 37,0 ℃ |
Kapadetan | 1,320±0,06 g/cm3 |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Pareum-Bodas mun Konéng Bubuk Padet |
1 H NMR Spéktrum | Konsisten Jeung Struktur |
Purity / Métode Analisis | > 98,0% (HPLC) |
Leungitna dina Drying | <1,00% |
Total Kotoran | <2.00% |
Standar tés | Standar Perusahaan |
Pamakéan | Panengah/Impurity of Lenvatinib Mesylate (CAS: 857890-39-2) |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap
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Métil 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) mangrupikeun perantara Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib mangrupikeun ubar kanker tiroid anu dikembangkeun ku Eisai Corporation of Japan (Kode: E7080), kagolong kana inhibitor multi-reséptor tirosin kinase (RTK) lisan sareng tiasa ngahambat kagiatan kinase faktor pertumbuhan endothelial vaskular Reséptor R1 (FLT1), VEG-FR2 (KDR), R3 (FLT4).Lenvatinib ogé bisa ngahambat involvement of RTKs séjén dina angiogenesis patologis, tumuwuhna tumor, sarta progression kanker iwal fungsi sélular normal maranéhanana kaasup fibroblast growth factor (FGF) reséptor FGFR1, 2, 3, jeung 4;reséptor faktor pertumbuhan turunan trombosit (PDGFR [alfa]), KIT, sareng RET.[Indikasi]: Lenvatinib cocog pikeun pengobatan pasien kanker tiroid kambuh lokal atanapi tipe metastasis, tipe progressivity jeung tipe differentiated iodin-refractory radioaktif.
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