N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Purity> 99,0% (HPLC) Afatinib Dimaleate Panengah Pabrik Gambar Diulas

N-(3-Chloro-4-Fluorophenyl) -7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Purity> 99,0% (HPLC) Afatinib Dimaleate Intermediate Factory

Katerangan pondok:

Ngaran Kimia: N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine

CAS: 162012-67-1

Kamurnian: > 99,0% (HPLC)

Penampilan: Lampu Konéng ka Konéng Bubuk

Panganteur Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Katerangan:

Panganteur Pasokan Kimia Ruifu of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Dietil Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Asam Dietilphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-hiji CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5

Sipat Kimia:

Ngaran Kimia	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine
sinonim	N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitro-4-Quinazolinamine;(3-Chloro-4-Fluorophenyl)(7-Fluoro-6-Nitroquinazolin-4-yl)amin;4-(3-Chloro-4-Fluoroanilino) -7-Fluoro-6-Nitroquinazoline;Afatinib panengah A
Nomer CAS	162012-67-1
Nomer CAT	RF-PI2026
Status saham	Dina Stok, Skala Produksi Nepi ka Ton
Formula Molekul	C14H7ClF2N4O2
Beurat Molekul	336.68
Sensitipitas	Sensitip hawa, Sensitip Panas
Titik lebur	242,0 ~ 244,0 ℃
Titik didih	489 ℃
Kapadetan	1.616
merek	Kimia Ruifu

spésifikasi:

Barang	spésifikasi
Penampilan	Lampu Konéng ka Konéng Bubuk
Purity / Métode Analisis	> 99,0% (HPLC)
Leungitna dina Drying	<0,50%
Résidu on Ignition	<0,20%
Zat Patali
Najis individu	<0,50%
Total Kotoran	<1,00%
Logam beurat	≤20ppm
Spéktrum Infrabeureum	Conforms kana Struktur
Proton NMR Spéktrum	Conforms kana Struktur
Standar tés	Standar Perusahaan
Pamakéan	Panganteur Afatinib Dimaleate (CAS: 850140-73-7)

Paket & Panyimpenan:

Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang

Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap

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N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine (CAS: 162012-67-1) mangrupa perantara dina sintésis Afatinib Dimaleate (CAS: 850140-73-7) .Afatinib Dimaleate mangrupikeun bentuk uyah tina Afatinib.Afatinib nyaéta generasi kadua, dikaluarkeun sacara oral, sambetan teu bisa malik tina kulawarga ErbB kinase tirosin.Mékanisme ActionAfatinib downregulates ErbB signalling ku kovalén ngariung kana domain kinase of reséptor faktor pertumbuhan épidermal (EGFR), reséptor faktor pertumbuhan épidermal manusa (HER) 2 na HER4, hasilna inhibisi teu bisa balik ti tirosin kinase autophosphorylation;éta ogé ngahambat transphosphorylation of HER3.Afatinib disatujuan salaku monoterapi pikeun pengobatan EGFR tirosin kinase inhibitor (TKI) -naif sawawa jeung lokal maju atawa DefinitionChEBI: A uyah maleate diala ku ngagabungkeun afatinib jeung dua equivalents molar asam maleat.Dipaké pikeun pengobatan lini kahiji pasien kalayan kanker paru sél non-leutik métastatik.