Remdesivir Intermediate CAS 1911578-98-7 2-Étilbutil ((S)-(perfluorophenoxy)(fenoksi)fosforil)-L-alaninat
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Ngaran Kimia | 2-Étilbutil ((S)-(perfluorofenoksi)(fenoksi)fosforil)-L-alaninat |
sinonim | N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-étilbutil éster;Remdesivir panengah;Remdesivir-001;Remdesivir Impurity 21 |
Nomer CAS | 1911578-98-7 |
Nomer CAT | RF-PI303 |
Status saham | Dina Stok, Skala Produksi Nepi ka Ratusan Kilogram |
Formula Molekul | C21H27N2O7P |
Beurat Molekul | 495.38 |
Kapadetan | 1,2 g/cm3 |
Titik lebur | 92,0 ~ 96,0 ℃ (lit.) |
Titik didih | 356,7 ℃ dina 760 mmHg |
Kaayaan Pangiriman | Dikirim dina Suhu Ambient |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bodas ka Pareum-Bodas Bubuk |
Spéktrum Infrabeureum | Conforms kana Struktur |
Kasucian | ≥99,0% |
Leungitna dina Drying | ≤0,50% |
Najis Tunggal | ≤0,50% |
Total Kotoran | ≤1,0% |
Logam beurat | ≤20ppm |
Standar tés | Standar Perusahaan |
Pamakéan | Panganteur Remdesivir (CAS 1809249-37-3) |
Bungkusan: Botol, kantong Aluminium foil, kardus drum, 25kg / Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya, Uap jeung infestation hama.
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) mangrupa perantara konci canggih dina persiapan analog Remdesivir patali.Remdesivir mangrupikeun prodrug monophosphoramidate tina analog adénosin, mangrupikeun agén antiviral spéktrum lega anu panalungtikan kalayan kagiatan in vitro ngalawan SARS coronavirus, MERS coronavirus sareng, langkung énggal, Covid-19.Remdesivir utamina dikembangkeun salaku pangobatan pikeun inféksi filovirus sapertos panyakit virus Ebola atanapi virus Marburg.Salajengna, Remdesivir kapanggih nunjukkeun kagiatan antiviral ngalawan virus RNA untaian tunggal sanés sapertos virus respiratory syncytial, virus Nipah, virus Hendra, virus Junin, virus demam Lassa sareng coronaviruses (kalebet virus MERS sareng SARS).Anyar-anyar ieu ditaliti salaku ubar anu ngajangjikeun pikeun pengobatan COVID-19 (virus jinis SARS anyar).Remdesivir, dikembangkeun ku Gilead Sciences, mangrupikeun prodrug adénosin anu métabolismena kana bentuk aktifna GS-441524 anu ngaganggu tindakan polimérase RNA-gumantung RNA virus sareng ngahindarkeun proofreading ku exoribonuclease virus (ExoN), nyababkeun panurunan dina produksi RNA virus.