Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Purity> 99,0% (HPLC) Pabrik Kualitas Luhur
Pasokan Sitagliptin Phosphate Monohydrate Related Intermediate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Asam Trifluorophenylacetic CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Asam Butyric CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Ngaran Kimia | 3- (Trifluorométil) -5,6,7,8-tetrahydro- [1,2,4] triazolo [4,3-a] pyrazine Hydrochloride |
sinonim | Sitagliptin Triazole Hydrochloride;Sitagliptin Intermediate A |
Nomer CAS | 762240-92-6 |
Nomer CAT | RF-PI1193 |
Status Saham | Dina Stok, Skala Produksi Nepi ka Ton |
Formula Molekul | C6H7F3N4·HCl |
Beurat Molekul | 228.60 |
Titik Lebur | 236,0 ~ 246,0 ℃ |
Kalarutan | Leyur dina Métanol |
merek | Kimia Ruifu |
Barang | spésifikasi |
Penampilan | Bodas ka Pareum-Bodas Bubuk Kristal |
Idéntifikasi ku HPLC | Waktu ingetan sampel saluyu sareng standar rujukan |
Idéntifikasi ku IR | matuh |
Leungitna dina Drying | <0,50% |
Zat Patali | |
Sakur Najis Tunggal | <0,50% |
Total Kotoran | <1,00% |
Logam beurat | <20ppm |
Purity / Métode Analisis | > 99,0% (HPLC) |
Standar tés | Standar Perusahaan |
Pamakéan | Panganteur Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Bungkusan: Botol, kantong Aluminium foil, 25kg / Karton Drum, atawa nurutkeun sarat customer urang.
Kaayaan Panyimpenan:Simpen dina wadah anu disegel dina tempat anu tiis sareng garing;Ngajaga tina cahaya sareng Uap.
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3-(Trifluoromethyl) -5,6,7,8-tetrahydro- [1,2,4] triazolo [4,3-a] pyrazine Hydrochloride (CAS: 762240-92-6) nyaéta perantara tina Sitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), anu mangrupa inhibitor DPP4 selektif oral-bioavailable anu kapanggih ngaliwatan optimasi kelas β-aminoacid-turunan DPP4 inhibitor.Éta nurunkeun kagiatan DPP4 sacara terus-terusan saatos administrasi sakali sadinten, ngajaga tingkat sirkulasi GIP sareng GLP1 utuh saatos tuang dina studi akut sareng kronis sareng ngirangan tingkat glukosa getih tanpa paningkatan anu signifikan dina hipoglisemia.Sitagliptin Phosphate (STG) dianggo pikeun ngubaran DM tipe 2 sabab ningkatkeun kontrol glikemik ku cara ningkatkeun tingkat hormon incretin aktif, GLP-1 (péptida-1) sareng GIP (péptida insulinotropik anu gumantung kana glukosa).STG disatujuan ku FDA dina 2006.
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Sitagliptin CAS 486460-32-6 Kemurnian> 99,0% (HPLC...
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Sitagliptin Phosphate Monohydrate CAS 654671-77...
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2,4,5-Asam Trifluorophenylacetic CAS 209995-38-...
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
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Sitagliptin Triazole Hydrochloride CAS 762240-9...
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Sitagliptin Phosphate Monohydrate Intermediate...