1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 Purity>98.0% (HPLC) Almotriptan Malate Intermediate Factory
Ruifu Chemical Supply Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Jina la Kemikali | 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine |
Visawe | N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine;1-((4-Nitrobenzyl)sulfonyl)pyrrolidine |
Nambari ya CAS | 340041-91-0 |
Nambari ya CAT | RF-PI1959 |
Hali ya Hisa | Katika Hisa, Uzalishaji Umeongezeka Hadi Tani |
Mfumo wa Masi | C11H14N2O4S |
Uzito wa Masi | 270.30 |
Chapa | Ruifu Chemical |
Kipengee | Vipimo |
Njia ya Usafi / Uchambuzi | >98.0% (HPLC) |
Kupoteza kwa Kukausha | <1.00% |
Kiwango cha Mtihani | Kiwango cha Biashara |
Matumizi | Kati ya Almotriptan Malate (CAS: 181183-52-8) |
Kifurushi: Chupa, begi ya karatasi ya Alumini, Ngoma ya 25kg/Cardboard, au kulingana na mahitaji ya mteja
Hali ya Uhifadhi:Hifadhi kwenye vyombo vilivyofungwa mahali pa baridi na kavu;Kinga kutoka kwa mwanga na unyevu
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1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) ni ya kati katika Maandalizi ya Almotriptan Malate (CAS: 181183-52-8).Almotriptan Malate ni agonisti wa aina ndogo za vipokezi vya serotonini (5-HT) 5-HT.1Bna 5-HT1D(IC50s=12 na 13 nM, kwa mtiririko huo, katika jaribio la kumfunga radioligand).Almotriptan Malate (LAS 31416) ni kipokezi cha kuchagua cha 5-hydroxytryptamine1B/1D (5-HT1B/1D), kinachotumiwa kutibu mashambulizi ya Kipandauso kwa watu wazima.Almotriptan, iliyouzwa mwaka wa 2000, ina upatikanaji wa juu zaidi wa bioavailability kati ya triptan zote.Imechangiwa na MAO-A na CYP3A4, kwa hivyo ina wasifu wa athari nzuri zaidi ikilinganishwa na Sumatriptan.