2-Methyltryptamine CAS 2731-06-8 Usafi >99.0% (HPLC) Panobinostat Ubora wa Juu wa Kiwanda cha Kati
Ugavi wa Watengenezaji Wenye Ubora wa Juu, Uzalishaji wa Biashara
Jina la Kemikali: 2-Methyltryptamine CAS: 2731-06-8
Jina la Kemikali | 2-Methyltryptamine |
Visawe | 2-Methylindole-3-Ethylamine;2-(2-Methyl-1H-indol-3-yl)ethanamine;3-(2-Aminoethyl)-2-Methylindole |
Nambari ya CAS | 2731-06-8 |
Nambari ya CAT | RF-PI1480 |
Hali ya Hisa | Katika Hisa, Uzalishaji Umeongezeka Hadi Tani |
Mfumo wa Masi | C11H14N2 |
Uzito wa Masi | 174.25 |
Kiwango cha kuyeyuka | 106.0 hadi 110.0℃ |
Kuchemka | 177℃/1.5mmHg(lit.) |
Chapa | Ruifu Chemical |
Kipengee | Vipimo |
Mwonekano | Brown Imara |
Njia ya Usafi / Uchambuzi | >99.0% (Eneo la HPLC) |
1-HNMR | Sambamba na Muundo |
Kupoteza kwa Kukausha | <1.00% |
Uchafu Mmoja | <0.50% |
Jumla ya Uchafu | <1.00% |
Metali Nzito (kama Pb) | <20ppm |
Kiwango cha Mtihani | Kiwango cha Biashara |
Matumizi | Wasaidizi wa Dawa;Panobinostat ya kati |
Kifurushi: Chupa, mfuko wa karatasi ya Alumini, Ngoma ya 25kg/Kadibodi, au kulingana na mahitaji ya mteja.
Hali ya Uhifadhi:Hifadhi kwenye vyombo vilivyofungwa mahali pa baridi na kavu;Kinga kutoka kwa mwanga na unyevu.
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2-Methyltryptamine (CAS: 2731-06-8) ni nyenzo muhimu ya kuanzia katika usanisi wa Panobinostat (LBH589) (CAS: 404950-80-7).Panobinostat ni kizuizi chenye nguvu cha histone deasetylases (HDACs), zenye thamani za Ki kuanzia 0.6 hadi 31 nM kwa HDAC1-11.Kupitia hatua hii, husababisha acetylation ya anuwai ya protini za seli, na kusababisha kukamatwa kwa mzunguko wa seli na apoptosis katika seli za saratani.Panobinostat ndicho kizuizi cha kwanza cha HDAC kilichoidhinishwa na FDA kwa matibabu ya myeloma nyingi.Panobinostat inauzwa kama Farydak, inatumika pamoja na Bortezomib (CAS: 179324-69-7) na Dexamethasone (CAS: 50-02-2) kutibu myeloma nyingi zilizorudi tena baada ya matibabu ya awali na Bortezomib na immunomodulator.
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