2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Purity ≥99.5% (GC) Sitagliptin Phosphate Monohydrate ya Kati
Ugavi Viti Vinavyohusiana vya Sitagliptin Phosphate Monohydrate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate ya Kati CAS 486460-21-3
Jina la Kemikali | 2,4,5-Trifluorophenylacetic Acid |
Nambari ya CAS | 209995-38-0 |
Nambari ya CAT | RF-PI1191 |
Hali ya Hisa | Katika Hisa, Uzalishaji Umeongezeka Hadi Tani |
Mfumo wa Masi | C8H5F3O2 |
Uzito wa Masi | 190.12 |
Kiwango cha kuyeyuka | 121.0 hadi 125.0℃ |
Umumunyifu | Mumunyifu katika Methanoli |
Chapa | Ruifu Chemical |
Kipengee | Vipimo |
Mwonekano | Poda Nyeupe hadi Nyeupe |
Njia ya Usafi / Uchambuzi | ≥99.5% (GC) |
Unyevu (KF) | ≤0.50% |
Mabaki kwenye Igniton | ≤0.50% |
Jumla ya Uchafu | ≤0.50% |
Kiwango cha Mtihani | Kiwango cha Biashara |
Matumizi | Kati ya Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Kifurushi: Chupa, mfuko wa karatasi ya Alumini, Ngoma ya 25kg/Kadibodi, au kulingana na mahitaji ya mteja.
Hali ya Uhifadhi:Hifadhi kwenye vyombo vilivyofungwa mahali pa baridi na kavu;Kinga kutoka kwa mwanga na unyevu.
2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) ni ya kati ya Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) hutumiwa kutibu DM aina 2 kwa sababu inaboresha udhibiti wa glycemic kwa kuongeza viwango vya homoni za incretin, GLP-1 (peptide-1) na GIP (peptidi ya insulinotropic inayotegemea glukosi).Uanzishaji wa incretins hizi katika seli za β-pancreatic husababisha kuongezeka kwa viwango vya cyclic adenosine monophosphate (cAMP) na kalsiamu ya ndani ya seli, na usiri wa insulini unaotegemea glukosi (2).Dawa hii ya hypoglycemic ni ya darasa jipya linaloitwa dipeptidyl peptidase IV inhibitors.STG iliidhinishwa na FDA mnamo 2006.