Lapatinib Intermediate CAS 231278-84-5 Purity >98.0% (HPLC)
Jina la Kemikali | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Visawe | Lapatinib ya kati 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Nambari ya CAS | 231278-84-5 |
Hali ya Hisa | Katika Hisa, Uzalishaji Umeongezeka Hadi Tani |
Mfumo wa Masi | C26H17ClFN3O3 |
Uzito wa Masi | 473.90 |
Kiwango cha kuyeyuka | 225.0 hadi 235.0℃ |
Msongamano | 1.407±0.06 g/cm3 |
Kielezo cha Refractive | 1.694 |
COA & MSDS | Inapatikana |
Asili | Shanghai, Uchina |
Chapa | Ruifu Chemical |
Kipengee | Vipimo |
Mwonekano | Poda Imara ya Manjano Iliyokolea hadi Manjano |
Njia ya Usafi / Uchambuzi | >98.0% (HPLC) |
Kiwango cha kuyeyuka | 225.0~235.0℃ |
Kupoteza kwa Kukausha | <1.00% |
Mabaki kwenye Kuwasha | <0.50% |
Jumla ya Uchafu | <2.00% |
Metali Nzito (kama Pb) | <20ppm |
Kiwango cha Mtihani | Kiwango cha Biashara |
Matumizi | API ya kati (CAS 388082-77-7) |
Kifurushi: Chupa, begi ya karatasi ya Alumini, Ngoma ya 25kg/Cardboard, au kulingana na mahitaji ya mteja
Hali ya Uhifadhi:Hifadhi kwenye vyombo vilivyofungwa mahali pa baridi na kavu;Kinga kutoka kwa mwanga na unyevu
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5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) ni API ya kati (CAS 388082-77-7 )(CAS 388082-77-7) ni dawa inayolenga saratani ya matiti iliyotengenezwa na British GlaxoSmithKline Co. Ni kizuizi cha tyrosine kinase ambacho kinaweza kuzuia shughuli ya tyrosine kinase ya vipokezi vya ukuaji wa epidermal 1 na 2 (ErbB1, ErbB2).Inaweza kipekee kutenda kwa njia mbalimbali, kuhakikisha kwamba seli za saratani ya matiti haziwezi kupokea ishara za ukuaji.Inazuia maeneo ya ndani ya EGFR (ErbB-1) na HER2 (ErbB-2) ATP, kuzuia fosforasi ya seli ya tumor na uanzishaji, kuzuia ishara za udhibiti wa chini kupitia homogeneity na heterogeneity ya EGFR (ErbB-1) na HER2 (ErbB-1) dimerization.
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