tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Purity >98.0% (HPLC) Palbociclib Intermediate Factory

Maelezo Fupi:

Jina la Kemikali: tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate

Majina mengine: 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine

CAS: 571189-16-7

Usafi: >98.0% (HPLC)

Muonekano: Kahawia Isiyokolea hadi Poda ya Hudhurungi

Kati ya Palbociclib (CAS: 571190-30-2)

E-Mail: alvin@ruifuchem.com

Tutumie barua pepe

Maelezo ya Bidhaa

Bidhaa Zinazohusiana

Lebo za Bidhaa

Maelezo:

Ugavi wa Kemikali wa Ruifu Palbociclib Viatu Vinavyohusiana:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-moja CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Sifa za Kemikali:

Jina la Kemikali	tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate
Visawe	1-Boc-4-(6-Nitro-3-Pyridyl)piperazine;4-(6-Nitro-3-pyridinyl) -1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate
Nambari ya CAS	571189-16-7
Nambari ya CAT	RF-PI1850
Hali ya Hisa	Katika Hisa, Uzalishaji Umeongezeka Hadi Tani
Mfumo wa Masi	C14H20N4O4
Uzito wa Masi	308.33
Chapa	Ruifu Chemical

Vipimo:

Kipengee	Vipimo
Mwonekano	Kahawia Isiyokolea hadi Poda ya Hudhurungi
Njia ya Usafi / Uchambuzi	>98.0% (HPLC)
LCMS	Sambamba na Muundo
Kupoteza kwa Kukausha	<1.00%
Jumla ya Uchafu	<2.00%
Kiwango cha Mtihani	Kiwango cha Biashara
Matumizi	Kati ya Palbociclib (CAS: 571190-30-2)

Kifurushi na Hifadhi:

Kifurushi: Chupa, begi ya karatasi ya Alumini, Ngoma ya 25kg/Cardboard, au kulingana na mahitaji ya mteja

Hali ya Uhifadhi:Hifadhi kwenye vyombo vilivyofungwa mahali pa baridi na kavu;Kinga kutoka kwa mwanga na unyevu

Manufaa:

Maswali Yanayoulizwa Mara kwa Mara:

Maombi:

tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS: 571189-16-7) ni sehemu ya kati ya Palbociclib (CAS: 571190-30-2).Palbociclib (pia inajulikana kama nambari ya kiwanja PD-0332991) ni dawa ya majaribio ya matibabu ya saratani ya matiti inayotengenezwa na Pfizer.Ni kizuizi cha kuchagua cha kinasi zinazotegemea cyclin CDK4 na CDK6.Palbociclib huzuia kuendelea kwa mzunguko wa seli kutoka awamu ya G1 hadi S kwa kuzuia fosphorylation tegemezi ya CDK4/6 (RB) ya retinoblastoma (RB).Palbociclibhas imetumika kutibu saratani ya matiti ya HER2 hasi, kipokezi cha estrojeni (ER).