Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Purity >98.5% (HPLC) Kiwanda
Ugavi wa Kemikali wa Ruifu Olmesartan Medoxomil Unaopatana na Ubora wa Juu:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Asidi ya Trityl Olmesartan CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Jina la Kemikali | Trityl Olmesartan Ethyl Ester |
Visawe | Olmesartan Ethyl Ester Trityl Uchafu;Olmesartan Medoxomil Uchafu 30;4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl ]methyl]-1H-Imidazole-5-Carboxylic Acid Ethyl Ester;Ethyl 4-(2-hydroxypropan-2-yl)-2-Propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl )methyl)-1H-Imidazole-5-Carboxylate |
Nambari ya CAS | 144690-33-5 |
Nambari ya CAT | RF-PI1873 |
Hali ya Hisa | Katika Hisa, Uzalishaji Umeongezeka Hadi Tani |
Mfumo wa Masi | C45H44N6O3 |
Uzito wa Masi | 716.87 |
Kiwango cha kuyeyuka | 161℃ |
Msongamano | 1.18±0.1 g/cm3 |
Chapa | Ruifu Chemical |
Kipengee | Vipimo |
Mwonekano | Poda Nyeupe hadi Nyeupe |
Njia ya Usafi / Uchambuzi | >98.5% (HPLC) |
Maudhui ya Maji (KF) | <0.50% |
Mabaki kwenye Kuwasha | <0.20% |
Uchafu Ⅰ | <0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl ]methyl}-1H-imidazole-5-carboxylic ethyl ester |
Uchafu Ⅱ | <0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]- 4-yl]methyl}-1H-imidazole-5-carboxylic ethyl ester |
Uchafu Ⅲ | <0.50% 4-Isopropenyl-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl]-4-yl]methyl}-1H -imidazole-5-carboxylic ethyl ester |
Uchafu Mwingine wa Juu Zaidi | <1.00% |
Jumla ya Uchafu | <1.50% |
Kiwango cha Mtihani | Kiwango cha Biashara |
Kifurushi: Chupa, begi ya karatasi ya Alumini, Ngoma ya 25kg/Cardboard, au kulingana na mahitaji ya mteja
Hali ya Uhifadhi:Hifadhi kwenye vyombo vilivyofungwa mahali pa baridi na kavu;Kinga kutoka kwa mwanga na unyevu
Trityl Olmesartan Ethyl Ester (CAS: 144690-33-5) ni uchafu wa Olmesartan Medoxomil (CAS: 144689-63-4).Olmesartan Medoxomil ni kipinzani cha vipokezi vya angiotensin II kinachotumika kutibu shinikizo la damu, Hutumika kama dawa ya kupunguza shinikizo la damu.Olmesartan hufanya kazi kwa kuzuia kumfunga angiotensin II kwa vipokezi vya AT1 kwenye misuli ya mishipa.Kwa kuzuia kumfunga badala ya awali ya angiotensin II, Olmesartan inhibitisha maoni hasi ya udhibiti juu ya usiri wa renin.Olmesartan Medoxomil ilizinduliwa nchini Marekani kama Benicar@, matibabu yanayosimamiwa kwa mdomo kwa shinikizo la damu.Olmesartan Medoxomil huamilishwa haraka na kikamilifu na hidrolisisi ya ester kwa metabolite yake hai, olmesartan, wakati wa kunyonya kutoka kwa njia ya utumbo.