Telbivudine CAS 3424-98-4 Purity ≥99.0% (HPLC) HBV Replication Inhibitor Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Telbivudine (2'-Deoxy-L-Thymidine) (CAS: 3424-98-4) with high quality. Telbivudine, an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication. Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service. Purchase Telbivudine or other products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | Telbivudine |
| Synonyms | 2'-Deoxy-L-Thymidine; L-Thymidine; beta-L-Thymidine; β-L-Thymidine; Epavudine; NV 02B; Sebivo; 1-(2-Deoxy-β-L-Erythro-Pentofuranosyl)-5-Methyl-2,4(1H,3H)-Pyrimidinedione; 1-[(2S,4R,5S)-4-Hydroxy-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-5-Methylpyrimidine-2,4(1H,3H)-Dione |
| Stock Status | In Stock, Production Capacity 15 Tons per Year |
| CAS Number | 3424-98-4 |
| Molecular Formula | C10H14N2O5 |
| Molecular Weight | 242.23 g/mol |
| Melting Point | 185.0~190.0℃ |
| Density | 1.452±0.06 g/cm3 |
| Store Under Inert Gas | Store Under Inert Gas |
| Sensitive | Air Sensitive, Heat Sensitive |
| Solubility H2O | Soluble 10mg/mL (Clear Solution) |
| Storage Temp. | Store Long-term at 2~8℃ |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
API (Active Pharmaceutical Ingredient); Antiviral Agents |
| Caution | Not Intended for Human Use. For Research Use Only. |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White Fine Powder | White Fine Powder |
| Solubility | Clear, Colorless in Water/Very Slightly Soluble | Conforms |
| Identify (H NMR) | Conforms to Structure | Conforms |
| Melting Point | 185.0~190.0℃ | 186.0~188.0℃ |
| Specific Rotation [α]20/D | -19.0° ~ -17.0° (C = 1 in H2O) | -18.4° |
| Loss on Drying | ≤0.50% | 0.12% |
| Residue on Ignition | ≤0.20% | Conforms |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Largest Impurities | ≤0.30% | 0.04% |
| Telbivudine Purity | >99.0% (HPLC) | 99.9% |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | A Potent Antiviral Inhibitor of Hepatitis B Virus (HBV) Replication | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | UV9048500 |
| HS Code | 2934993090 |
Telbivudine (2'-Deoxy-L-Thymidine) (CAS: 3424-98-4) is a β-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5'-triphosphate.
Telbivudine (2'-Deoxy-L-Thymidine) (CAS: 3424-98-4) is an antiviral drug used in the treatment of hepatitis B virus (HBV) infection. Clinical trials have shown it to be significantly more effective than Lamivudine or Adefovir, and less likely to cause resistance. For the treatment of chronic hepatitis B in adult and adolescent patients ≥16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
