TEMPO Free Radical CAS 2564-83-2 Purity >99.0% (GC)

2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical (abbreviated as TEMPO Free Radical) (CAS: 2564-83-2) is a piperidine nitroxide radical. TEMPO has the functions of capturing free radicals and quenching singlet oxygen, and is a very effective oxidation catalyst, which can oxidize primary alcohols to aldehydes and secondary alcohols to ketones. Due to the steric hindrance effect of the four methyl groups, TEMPO is relatively stable to light and heat and is a very effective oxidation catalyst, which can oxidize primary and secondary alcohols to the required carbonyl compounds. It has the characteristics of high yield, good selectivity, good stability and recyclability. TEMPO is a stable radical prepared through the oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy. TEMPO is widely used as a radical trap, as a structural probe for biological systems in conjunction with electron spin resonance spectroscopy, as a reagent in organic synthesis, and as a mediator in controlled free radical polymerization. TEMPO is used as a catalyst in organic synthesis and for the oxidation of primary alcohols to aldehydes. It finds use in the chemical industry for conversion of bisnoralcohol (a steroid) to bisnoraldehyde. It acts as a free radical scavenger, as a mediator in controlled radical polymerization and as a structural probe in electron spin resonance spectroscopy.  Further, it is involved in the preparation of (S)-(+)-2-Methylbutanal from (S)-(-)-2-Methyl-1-butanol.