8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS 100331-89-3 Indacaterol Maleate Intermediate Factory
Commercial Supply Indacaterol Maleate (CAS: 753498-25-8) Mga Kaugnay na Intermediate:
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS: 312753-53-0
8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS: 100331-89-3
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone CAS: 173140-90-4
Pangalan ng kemikal | 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline |
Mga kasingkahulugan | 8-(Benzyloxy)-5-(2-Bromoacetyl)quinolin-2(1H)-isa;5-(Bromoacetyl)-8-(Phenylmethoxy)-2(1H)-Quinolinone;5-(2-Bromo-1-Oxoethyl)-8-Benzyloxy-2(1H)-Quinolinone;5-Bromoacetyl-8-Benzyloxycarbostyril |
Numero ng CAS | 100331-89-3 |
Katayuan ng Stock | Sa Stock, Production Scale Hanggang Daan-daang Kilogramo |
Molecular Formula | C18H14BrNO3 |
Molekular na Timbang | 372.21 |
Temperatura ng pagkatunaw | 192.0~194.0 ℃ |
Punto ng pag-kulo | 602.6±55.0℃ sa 760 mmHg |
Densidad | 1.479±0.06 g/cm3 |
Tatak | Ruifu Chemical |
item | Mga pagtutukoy |
Hitsura | Puti-Puti hanggang Dilaw na Pulbos |
Kadalisayan / Paraan ng Pagsusuri | >95.0% (HPLC) |
Kahalumigmigan (KF) | <1.00% |
Nalalabi sa pag-aapoy | <0.50% |
Karumihan A | <3.00% (5-Acetyl-8-(Benzyloxy)quinolin-2(1H)-one) |
Anumang Iba Pang Iisang Karumihan | <1.50% |
Kabuuang mga Dumi | <5.00% |
Infrared Spectrum | Naaayon sa Istraktura |
Pamantayan sa Pagsubok | Enterprise Standard |
Paggamit | Indacaterol Maleate (CAS: 753498-25-8) Intermediate |
Package:Bote, Aluminum foil bag, 25kg/Cardboard Drum, o ayon sa pangangailangan ng customer.
Kondisyon ng Imbakan:Panatilihing sarado nang mahigpit ang lalagyan at iimbak sa isang malamig, tuyo at mahusay na maaliwalas na bodega na malayo sa mga hindi tugmang sangkap.Protektahan mula sa liwanag at kahalumigmigan.
Pagpapadala:Ihatid sa buong mundo sa pamamagitan ng hangin, sa pamamagitan ng FedEx / DHL Express.Magbigay ng mabilis at maaasahang paghahatid.
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Ang Shanghai Ruifu Chemical Co., Ltd. ay ang nangungunang tagagawa at supplier ng 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline (CAS: 100331-89-3) na may mataas na kalidad, ito ay isang intermediate na karaniwang nasa synthesis ng Indacaterol Maleate (CAS: 753498-25-8).
Ang Indacaterol Maleate (CAS: 753498-25-8) ay isang bago, ultra-long-acting, mabilis na pagsisimula ng β(2)-adrenoceptor agonist at bronchodilator.Ginagamit ito sa paggamot ng chronic obstructive pulmonary disease (COPD) at hika.Inaprubahan ng European Medicines Agency (EMA) ang indacaterol bilang gamot noong 2009 sa ilalim ng Onbrez trade name habang sa United States inaprubahan ito ng Food and Drug Administration sa ilalim ng trade name na Arcapta noong 2011. Ang gamot ay ginawa bilang maleate salt form nito.Gayundin, ang indacaterol ay isang chiral molecule;gayunpaman, tanging ang purong R-enantiomer lamang ang ipinamamahagi.
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