trans-4-Methoxycinnamic Acid CAS 943-89-5 Purity >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of trans-4-Methoxycinnamic Acid (CAS: 943-89-5) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase trans-4-Methoxycinnamic Acid, Please contact: alvin@ruifuchem.com
| Chemical Name | trans-4-Methoxycinnamic Acid |
| Synonyms | 4-Methoxycinnamic Acid; (E)-4-methoxycinnamic Acid; trans-O-Methyl-p-Coumaric Acid; trans-3-(4-Methoxyphenyl)acrylic Acid; (E)-3-(4-Methoxyphenyl)acrylic Acid; p-Methoxy-trans-Cinnamic Acid; 4-Methoxy-trans-Cinnamic Acid |
| Stock Status | In Stock, Commercial Scale |
| CAS Number | 943-89-5 |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.19 g/mol |
| Melting Point | 170.0~175.0℃ |
| Density | 1.195±0.06 g/cm3 |
| Sensitive | Light Sensitive |
| Solubility | Soluble in Ethanol, Ethyl Acetate and Other Organic Solvents. |
| Storage Temp. | Cool & Dry Place |
| COA & MSDS | Available |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | White to Off-White Crystals | White Crystals |
| Melting Point | 170.0~175.0℃ | 171.2~173.0℃ |
| Loss on Drying | <0.50% | 0.31% |
| Residue on Ignition | <0.20% | 0.11% |
| Total Aldehyde Content | <0.20% | <0.20% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.54% |
| Infrared Spectrum | Conforms to Structure | Complies |
| 1 H NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
WGK Germany 3
RTECS UD3391300
FLUKA BRAND F CODES 8
TSCA Yes
Hazard Class IRRITANT
trans-4-Methoxycinnamic Acid (CAS: 943-89-5), Esters derived from trans-4-methoxycinnamic acid are effective absorbers of UV radiation. Employed in organic synthesis of pharmaceutical intermediates, synthetic anti-adrenergic drugs esmolol, cosmetics ultraviolet absorption. Also used as a chemical reagent.
At present, the most commonly used 4-Methoxycinnamic Acid sunscreen agent is p-Methoxycinnamate octyl, which is a colorless or light yellow liquid, insoluble in water, soluble in organic solvents such as ethanol and ethyl acetate, It has no irritation to the skin, has high safety in use, and has high ultraviolet absorption rate for UVB area, can effectively prevent 280-330mm ultraviolet rays, and has high absorption rate. It is; it can effectively prevent skin redness and sunburn. At present, this raw material is widely used in many sunscreen cosmetics in various countries. It is obtained by the reaction of p-Methoxybenzaldehyde and Malonic Acid.
4-Methoxycinnamic Acid synthesis: In a 25-mL, round bottomed flask, 4-Methoxybenzaldehyde (0.804 mL, 6.61 mmol) (3), Malonic Acid (1.75 g, 16.8 mmol), and β-Alanine (0.10 g, 1.12 mmol) were dissolved in pyridine (3.0 mL, 37.1 mmol) and heated under reflux for 90 minutes. After cooling to room temperature, the reaction mixture was placed in an ice bath and 8.0 mL of concentrated HCl was slowly added. The resulting white precipitate was collected by vacuum filtration, washed with cold water (2 x 10mL) and dried thoroughly. The product was recrystallized from absolute ethanol (~20 mL).
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