trans-4-Methylcyclohexyl Isocyanate CAS 32175-00-1 Purity >98.0% (GC)

Short Description:

trans-4-Methylcyclohexyl Isocyanate

CAS: 32175-00-1

Purity: >98.0% (GC)

Appearance: Colorless to Light Yellow Liquid

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of trans-4-Methylcyclohexyl Isocyanate (CAS: 32175-00-1) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase trans-4-Methylcyclohexyl Isocyanate, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	trans-4-Methylcyclohexyl Isocyanate
Synonyms	trans-4-Methylcyclohexylisocyanate; trans-4-Methyl Cyclo Hexane Isocyanate; trans-1-Isocyanato-4-Methyl-Cyclohexane; Isocyanic Acid trans-4-Methylcyclohexyl Ester; (1r,4r)-1-Isocyanato-4-Methylcyclohexane
Impurity	Glimepiride Impurity 7
Stock Status	In Stock
CAS Number	32175-00-1
Molecular Formula	C8H13NO
Molecular Weight	139.19 g/mol
Boiling Point	65℃/6mmHg
Density	1.04
COA & MSDS	Available
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	Colorless to Light Yellow Liquid	Complies
Purity / Analysis Method	>98.0% (GC)	99%
Infrared Spectrum	Conforms to Structure	Complies
Proton NMR Spectrum	Conforms to Structure	Complies
Conclusion	The product has been tested & complies with the specifications

Package/Storage/Shipping:

Package: Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from sunshine; avoid fire; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Application:

trans-4-Methylcyclohexyl Isocyanate (CAS: 32175-00-1) is used as an intermediate for the drug Glimepiride. Glimepiride is a third-generation sulfonylurea long-acting antidiabetic drug, the main mechanism of its hypoglycemic effect is to stimulate the secretion of insulin by pancreatic beta cells, and to improve the sensitivity of the surrounding tissues to insulin. This product and insulin receptor binding and dissociation rate than glibenclamide for faster, less cause severe hypoglycemia. Its mechanism of action is through binding to a sulfonylurea receptor (a protein with a relative molecular mass of 6.5 × 104) on the surface of pancreatic β-cells, which binds to ATP-sensitive K +(KATP). The channels are coupled to cause the KATP channel to close, causing depolarization of the cell membrane, opening the voltage-dependent calcium channel, and the influx of Ga2 + to promote the release of insulin and inhibit the synthesis of hepatic glucose.