Trimethylsilylacetylene CAS 1066-54-2 Assay ≥98.0% (GC) High Purity

Precursor for Organic Synthesis:
Trimethylsilylacetylene (Ethynyltrimethylsilane; TMS-Acetylene) (CAS: 1066-54-2) serves as a versatile building block for organic synthesis due to the presence of the reactive ethynyl (C≡C) group. This group readily undergoes various reactions, allowing researchers to synthesize complex organic molecules with diverse functionalities.
Click Chemistry: Trimethylsilylacetylene participates in click chemistry reactions, a powerful tool for rapid and efficient formation of specific molecular bonds.
Sonogashira Coupling: This coupling reaction utilizes Trimethylsilylacetylene as a source of the ethynyl group, enabling the formation of carbon-carbon bonds between various organic fragments.
Modification of Biomolecules:
The ethynyl group in Trimethylsilylacetylene facilitates the selective modification of biomolecules, like proteins and nucleic acids. This modification allows researchers to:
Introduce Fluorescent Tags: Attaching fluorescent groups through the ethynyl moiety enables researchers to track and visualize the biomolecule within a cell.
Probe Biomolecular Interactions: By incorporating Trimethylsilylacetylene-derived tags, scientists can investigate interactions between biomolecules, providing insights into cellular processes.
Material Science Applications:
The unique properties of Trimethylsilylacetylene make it valuable in material science research for the development of:
Polymers: Incorporation of Trimethylsilylacetylene units into polymer chains can enhance their thermal stability, mechanical properties, and conductivity.
Organic Electronics: Trimethylsilylacetylene serves as a precursor for the synthesis of organic light-emitting diodes (OLEDs) and organic solar cells due to its ability to form conjugated structures.