Tris-HCl CAS 1185-53-1 Purity 99.50%~101.0% (Titration) Biological Buffer Molecular Biology Grade Ultrapure Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Tris-HCl (CAS: 1185-53-1) with high quality, commercial production. Welcomed to order. Please contact: alvin@ruifuchem.com
Chemical Name | Tris-HCl |
Synonyms | Tris Hydrochloride; Tris(hydroxymethyl)aminomethane Hydrochloride; Trimethylolaminomethane Hydrochloride; Trometamol Hydrochloride |
CAS Number | 1185-53-1 |
CAT Number | RF-PI1642 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C4H11NO3·HCl |
Molecular Weight | 157.59 |
Density | 1.05 g/mL at 20℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Grade | Molecular Biology Grade, Ultrapure |
Appearance | White Crystalline Powder |
Purity / Analysis Method | 99.50%~101.0% (by Titration 0.1 N NaOH / Dried Basis) |
Useful pH Range | 7.2~9.0 |
Melting Point | 149.0~151.0℃ |
Loss on Drying | ≤0.30% (105℃, 3h) |
Insoluble Matter | ≤0.03% |
Sulphated Ash | ≤0.05% |
Heavy Metals (as Pb) | ≤0.0005% |
pH (1.0% aqueous) | 4.2~5.0 |
Iron (Fe) | ≤0.0005% |
Copper (Cu) | ≤0.0001% |
Sulfate (SO4) | ≤0.01% |
Chloride (Cl) | ≤3ppm |
Nickel (Ni) | ≤3ppm |
UV Absorption/260nm | ≤0.06 (1.0M aqueous) |
UV Absorption/280nm | ≤0.05 (1.0M aqueous) |
Solubility in Water | Colorless and Clear Solution (1.0M aqueous) |
DNase, RNase, Protease | Not Detected |
IR | Confirm to Reference Standard |
Test Standard | Enterprise Standard |
Usage | Biological Buffer |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.


Tris-HCl (CAS: 1185-53-1) is used for biological buffer, used for protein crystal growth under different pH conditions, is a high quality buffer component used in SDS-PAGE. TRIS hydrochloride is a commonly used laboratory reagent. Highly water soluble. Useful pH Range 7.2~9.0. Tris-HCl is commonly used as a buffer component of phenol extraction of DNA or RNA and a buffering component of separating and stacking gels in the characterization of protein products by SDS-PAGE. Tris-HCL is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. Tris-HCl is also used as a titration standard. Commercial Purification (Downstream Processing) of Biological Molecules, Including Monoclonal Antibodies and Recombinant Proteins; Raw Materials for API / Drug Substance Formulation; Buffer for Molecular Biology and Clinical Diagnostic; Buffer for Analytical Chromatography, Electrophoresis and PCR.
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