1-Adamantanamin CAS 768-94-5 Soflik >98,0% (GC)
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Kimyoviy nomi | 1-adamantanamin |
Sinonimlar | Amantadin;1-aminoadamantan;1-adamantilamin;Adamantan-1-amin;Trisiklo[3.3.1.13,7]dekan-1-amin |
CAS raqami | 768-94-5 |
CAT raqami | RF-PI2286 |
Birja holati | Stokda, ishlab chiqarish quvvati 20 MT/oy |
Molekulyar formula | C10H17N |
Molekulyar og'irlik | 151.25 |
Zichlik | 1,066 g/sm3 |
Sezuvchan | Havoga sezgir |
Eruvchanlik (eriydi) | metanol;Organik erituvchilarda eriydi.Suvda erimaydi |
Brend | Ruifu kimyoviy |
Element | Texnik xususiyatlari |
Tashqi ko'rinish | Oqdan och sariq ranggacha kukun yoki kristall |
Soflik / Tahlil usuli | >98,0% (GC) |
Soflik / Tahlil usuli | 97,5~102,5% (HClO4 bilan titrlash) |
Erish nuqtasi | 207,0 ~ 209,0 ℃ |
Namlik (KF) | <0,50% |
Yonayotganda qoldiq | <0,50% |
Umumiy iflosliklar | <2,00% |
1 n HCl da eruvchanligi | Rangsizdan xira sariqgacha, tiniqdan biroz tumanligacha 5% oʻtadi |
Infraqizil spektr | Strukturaga mos keladi |
Proton NMR spektri | Strukturaga mos keladi |
Sinov standarti | Korxona standarti |
Foydalanish | Farmatsevtik vositachilar |
Paket: Shisha, alyuminiy folga sumkasi, 25kg / karton baraban yoki mijozning talabiga binoan
Saqlash holati:Salqin va quruq joyda yopiq idishlarda saqlang;Nur va namlikdan saqlang
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1-Adamantanamin, shuningdek, Amantadin yoki 1-Aminoadamantan yoki 1-Adamantylamine (CAS: 768-94-5) deb nomlanuvchi fosfinoil iminlarning enantioselektiv streker reaktsiyasida katalizator sifatida ishlaydi.Bundan tashqari, adamantan hosilalari, ya'ni Amantadin gidroxlorid sintezi uchun foydalidir.1-Adamantanamin farmatsevtika sanoatida antiviral va antiparkinsonik dori sifatida qo'llaniladigan adamantanlar sinfiga kiradi.Parkinsonizmni Levodopa, antikolinerjik preparatlar va amantadin kombinatsiyasi bilan davolash ushbu dorilarning har birini alohida ishlatishdan ko'ra yaxshiroq natijalar beradi.Bu NMDA glutamat retseptorlarining zaif antagonisti bo'lib, u dopaminning chiqarilishini oshiradi va dopaminning qayta qabul qilinishini bloklaydi.Preparat, shuningdek, miyadagi asab tugunlaridan norepinefrinning chiqarilishiga yordam berishi mumkin.U Parkinson kasalligining diskineziyasini davolashi va uzoq muddatli dopaminerjik davolanishdan keyin diskineziyani yaxshilashi mumkin.
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