Afatinib Dimaleate Intermediate CAS 314771-88-5 Soflik >99,0% (HPLC) zavodi
Afatinibning Ruifu kimyoviy ta'minoti oraliqlari
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hidroksitetrahidrofuran CAS 86087-23-2
(Dimetilamino)atsetaldegid Dietil Asetal CAS 3616-56-6
trans-4-Dimetilaminokrotonik kislota gidroxlorid CAS 848133-35-7
Dietilfosfonoasetik kislota CAS 3095-95-2
7-Ftor-6-Nitrokinazolin-4(1H)-bir CAS 162012-69-3
7-Xloro-6-Nitro-4-Hidroksikinazolin CAS 53449-14-2
N-(3-Chloro-4-Fluorofenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S) -N4-(3-Xloro-4-Ftorofenil)-7-((Tetrahidrofuran-3-il)oksi)kinazolin-4,6-DiaminCAS 314771-76-1
(S) -N-(3-Xloro-4-Fluorofenil)-6-Nitro-7-((Tetrahidrofuran-3-il)oksi)kinazolin-4-aminCAS 314771-88-5
Kimyoviy nomi | (S) -N-(3-Xloro-4-Fluorofenil)-6-Nitro-7-((Tetrahidrofuran-3-il)oksi)kinazolin-4-amin |
Sinonimlar | N-(3-Xloro-4-Ftorofenil)-6-Nitro-7-[(3S)-oksolan-3-il]oksikinazolin-4-Amin;7-((S)-tetrahidrofuran-3-iloksi)-4-(3-xloro-4-ftorofenil)amino-6-nitrokinazolin;Afatinib nopokligi |
CAS raqami | 314771-88-5 |
CAT raqami | RF-PI2027 |
Birja holati | Stokda, ishlab chiqarish hajmi tonnagacha |
Molekulyar formula | C18H14ClFN4O4 |
Molekulyar og'irlik | 404.78 |
Zichlik | 1,534±0,060 g/sm3 |
Brend | Ruifu kimyoviy |
Element | Texnik xususiyatlari |
Tashqi ko'rinish | Sariqdan och sariq ranggacha kukun |
Soflik / Tahlil usuli | >99,0% (HPLC) |
Quritishdagi yo'qotish | <0,50% |
Shaxsiy nopoklik | <0,50% |
Umumiy iflosliklar | <1,00% |
Og'ir metallar | ≤20ppm |
Sinov standarti | Korxona standarti |
Foydalanish | Afatinib Dimaleatning oraliq mahsuloti (CAS: 850140-73-7) |
Paket: Shisha, alyuminiy folga sumkasi, 25kg / karton baraban yoki mijozning talabiga binoan
Saqlash holati:Salqin va quruq joyda yopiq idishlarda saqlang;Nur va namlikdan saqlang
![1](https://a395.goodao.net/uploads/15.jpg)
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(S)-N-(3-xloro-4-fluorofenil)-6-Nitro-7-((Tetrahidrofuran-3-il)oksi)kinazolin-4-amin (CAS: 314771-88-5) ishlatiladi. Afatinib Dimaleat tayyorlash (CAS: 850140-73-7).Afatinib - saratonga qarshi maqsadli innovatsion dori, og'iz orqali yuboriladigan maqsadli preparatning yangi avlodi, dunyodagi birinchi saratonga qarshi maqsadli dori bo'lib, ErbB oilasiga qaytarilmas tarzda bog'lanadi va yanada samaraliroq va maqsadliroqdir. , saraton hujayralarining ko'payishini kamaytirish yoki kechiktirish.Afatinib tirozin kinaz inhibitörleri deb nomlanuvchi dorilar sinfiga kiradi.U ikkita chambarchas bog'liq bo'lgan oqsillar, epidermal o'sish omili retseptorlari (EGFR) va inson epidermal o'sish omili retseptorlari 2 (HER2) funktsiyasini blokirovka qilish orqali ishlaydi.Metastatik kichik hujayrali o'pka saratoni bilan og'rigan bemorlarni birinchi darajali davolash uchun ishlatiladi.Afatinib - saratonga qarshi maqsadli innovatsion dori, og'iz orqali yuboriladigan maqsadli preparatning yangi avlodi, dunyodagi birinchi saratonga qarshi maqsadli dori bo'lib, ErbB oilasiga qaytarilmas tarzda bog'lanadi va yanada samaraliroq va maqsadliroqdir. , saraton hujayralarining ko'payishini kamaytirish yoki kechiktirish.
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