Cyano-Irbesartan CAS 138401-24-8 Soflik >98,0% (HPLC) Irbesartan oraliq zavodi
Ruifu Chemical Supply Irbesartan Intermediate:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Tritil Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan yon zanjir gidroxlorid CAS 151257-01-1
Kimyoviy nomi | Siyano-irbesartan |
Sinonimlar | CyanoIrbesartan;Irbesartan siyano nopokligi;Irbesartan uglevodorod;Irbesartan nopokligi 6;2-Butil-3-[[2'-siyano-[1,1'-bifenil]-4-il]metil]-1,3-diazaspiro[4,4]non-1-en-4-on;4'-[(2-Butil-4-okso-1,3-diazaspiro[4,4]non-1-en-3-il)metil]-[1,1'-bifenil]-2-karbonitril |
CAS raqami | 138401-24-8 |
CAT raqami | RF-PI1892 |
Birja holati | Stokda, ishlab chiqarish hajmi tonnagacha |
Molekulyar formula | C25H27N3O |
Molekulyar og'irlik | 385,51 |
Zichlik | 1.15 |
Eruvchanlik (eriydi) | Metanol |
Brend | Ruifu kimyoviy |
Element | Texnik xususiyatlari |
Tashqi ko'rinish | Oqdan deyarli oq changdan kristallgacha |
Soflik / Tahlil usuli | >98,0% (HPLC) |
Tozalik | >97,0% (umumiy azot bilan) |
Erish nuqtasi | 91,0 dan 95,0 ℃ gacha |
Quritishdagi yo'qotish | <1,00% |
Yagona nopoklik | <1,00% |
Og'ir metallar | <20ppm |
Infraqizil spektr | Strukturaga mos keladi |
Sinov standarti | Korxona standarti |
Foydalanish | Irbesartanning oraliq / nopokligi (CAS: 138402-11-6) |
Paket: Shisha, alyuminiy folga sumkasi, 25kg / karton baraban yoki mijozning talabiga binoan
Saqlash holati:Salqin va quruq joyda yopiq idishlarda saqlang;Nur va namlikdan saqlang
![1](https://a395.goodao.net/uploads/15.jpg)
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Cyano-Irbesartan (CAS: 138401-24-8) Irbesartanning oraliq moddasi yoki nopokligi (CAS: 138402-11-6).Irbesartan angiotensin II (angiotensin II, Ang II) retseptorlari inhibitori hisoblanadi.Angiotensin II retseptorlari ikki turga bo'linadi: AT1 va AT2.Irbesartan AnglI ning AT1 retseptorlarini tanlab bloklaydi.U angning angga aylanishini inhibe qilishi mumkin, angiotensin-konvertatsiya qiluvchi ferment 1 retseptoriga (AT1) maxsus antagonize qilishi mumkin.AT1 ga antagonistik ta'sir AT2 dan 8500 baravar ko'p.Vazokonstriksiyani va aldosteronning chiqarilishini inhibe qilish orqali Ang va AT1 retseptorlarining bog'lanishini tanlab blokirovka qilishi mumkin, bu esa gipotenziv ta'sirga olib keladi.Ushbu mahsulot angiotensinga aylantiruvchi ferment (ACE), renin va boshqa gormon retseptorlarini inhibe qilmaydi, shuningdek, qon bosimi va natriy muvozanatini tartibga solish bilan bog'liq ion kanallarini inhibe qilmaydi.Irbesartan, shuningdek, miyokardning elektr o'zgarishini kamaytirishi mumkin, bu esa gipertenziya bilan og'rigan bemorlarning o'lim darajasini pasaytiradi.Hozirgi vaqtda u gipertenziya va yurak-qon tomir kasalliklarini davolash uchun eng samarali dori hisoblanadi.
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