b-D-ribofuranoza 1-atsetat 2,3,5-tribenzoat CAS 6974-32-9 tahlili ≥99,0% (HPLC) Klofarabin oraliq yuqori tozalik
Tijorat ta'minoti Clofarabine bilan bog'liq vositachilar:
Clofarabine CAS: 123318-82-1
2-Deoksi-2-ftor-1,3,5-tri-O-benzoil-a-D-arabinofuranoza CAS: 97614-43-2
b-D-ribofuranoza 1-atsetat 2,3,5-tribenzoat CAS: 6974-32-9
1,3,5-Tri-O-benzoil-D-ribofuranoza CAS: 22224-41-5
2,6-Dikloropurin CAS: 5451-40-1
Kimyoviy nomi | b-D-ribofuranoza 1-atsetat 2,3,5-tribenzoat |
Sinonimlar | 1-O-asetil-2,3,5-tri-O-benzoil-b-D-ribofuranoza |
CAS raqami | 6974-32-9 |
CAT raqami | RF-PI222 |
Birja holati | Stokda, ishlab chiqarish hajmi tonnagacha |
Molekulyar formula | C28H24O9 |
Molekulyar og'irlik | 504.49 |
Brend | Ruifu kimyoviy |
Element | Texnik xususiyatlari |
Tashqi ko'rinish | Oq yoki oq rangsiz kristall kukun |
Tahlil / tahlil usuli | ≥99,0% (HPLC) |
Erish nuqtasi | 126,0 ~ 133,0 ℃ |
Quritishda yo'qotish | ≤0,50% |
Yonayotganda qoldiq | ≤0,50% |
Umumiy iflosliklar | ≤1,00% |
Og'ir metallar | ≤20ppm |
Sinov standarti | Korxona standarti |
Foydalanish | Clofarabine CAS farmatsevtika oraliq mahsuloti: 123318-82-1 |
Paket: Shisha, alyuminiy folga sumkasi, karton baraban, 25kg / baraban yoki mijozning talabiga binoan.
Saqlash holati:Salqin va quruq joyda yopiq idishlarda saqlang;Yorug'lik, namlik va zararkunandalardan himoya qiling.
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b-D-ribofuranoza 1-atsetat 2,3,5-tribenzoat (CAS 6974-32-9) (Clofarabine CAS: 123318-82-1) ning oraliq mahsulotidir.Clofarabine (CAS: 123318-82-1) yangi purin nukleozid saratonga qarshi dorilar birinchi marta Amerika Qo'shma Shtatlari-Genzyme korporatsiyasining "Clofarabine" savdo nomlari bilan Top10 biofarmatsevtika kompaniyasi tomonidan muvaffaqiyatli ishlab chiqilgan.2004 yil 28 dekabrda AQSh oziq-ovqat va farmatsevtika idorasi (FDA) klofarabinni o'tkir limfotsitik leykemiya (ALL) bilan og'rigan bolalarga qo'llashni tasdiqlash uchun tezkor usuldan foydalangan;u yaxshi bardoshlik va oldindan aytib bo'lmaydigan salbiy reaktsiyalarsiz leykemiyani davolashda ajoyib samaraga ega.Vena ichiga yuborish yoki og'iz orqali yuborish orqali qo'llanilishi mumkin.Ushbu preparat o'n yildan ko'proq vaqt davomida bolalar leykemiyasini davolash uchun tasdiqlangan birinchi mahsulotdir.
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