Valsartan CAS 137862-53-4 Assay 98.0~102.0% API

Short Description:

Chemical Name: Valsartan

CAS: 137862-53-4

Appearance: White to Off-White Powder

Assay: 98.0~102.0%

API High Quality, Commercial Production. Antihypertensive

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer Supply Valsartan and Related Intermediates:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1

Chemical Properties:

Chemical Name	Valsartan
Synonyms	N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
CAS Number	137862-53-4
CAT Number	RF-API32
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C24H29N5O3
Molecular Weight	435.52
Melting Point	116.0~117.0℃
Stability	Hygroscopic
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Off-White Powder; Odorless, Hygroscopic
Identification	IR spectrum of the sample matches the reference standard spectrum
Identification	The retention time of the major peak in the chromatogram of the assay preparation corresponds to that of the standard preparation, as obtained in the Assay.
Solubility	Soluble in Methanol and Ethanol, Sparingly Soluble in Ethylacetate, Slightly Soluble in Dichloromethane, Insoluble in Water
Moisture (K.F)	≤1.00%
Absorbance (420mm)	≤0.02% (λ=420nm, C=0.05g/ml, L=1cm)
Residue on Ignition	≤0.10%
Heavy Metals	≤10ppm
D-Valsartan	≤1.00% (HPLC)
Related Substances (HPLC)
Butyryl-Valsartan	≤0.20%
Benzyl-Valsartan	≤0.10%
Single Unknown Inpurity	≤0.10%
Total Impurities	≤0.30% (Excluding D-Valsartan)
Residual Solvents (GC)
Methanol	≤3000ppm
Ethyl Acetate	≤5000ppm
N,N-Dimethylformamide	≤880ppm
Toluene	≤890ppm
Purity / Analysis Method	>99.0% (HPLC calculated on anhydrous, solvent-free basis)
Test Standard	United States Pharmacopoeia (USP)
Usage	Active Pharmaceutical Ingredient (API)

Valsartan (CAS: 137862-53-4) The Production Process Flow

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Valsartan (CAS: 137862-53-4) with high quality. Valsartan is a nonpeptide angiotensin II AT1 receptor antagonist, Antihypertensive, has the potential for high blood pressure and heart failure research.
Valsartan’s antihypertensive effects are stronger than those of enalapril and is suitable for treating hypertension, mild to moderate primary hypertension, and especially secondary hypertension caused by renal damage. It can significantly reduce proteinuria for hypertension patients with diabetes or normal liver functions, and it can promote uric acid and urinary sodium to protect the kidney. Valsartan is also suitable for reducing the cardiovascular mortality for high risk patients (left ventricular failure or dysfunction) after experiencing a heart attack.